ArticleBMC cancer2017
Cardiac metastasis from colon cancer effectively treated with 5-fluorouracil, leucovorin, and oxaliplatin (modified FOLFOX6) plus panitumumab: a case report.
Article in BMC cancer, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
11 citing papers in PubMed, 1 synthesis or guideline pooled it, 15 citations in OpenAlex.
- Cardiac metastases from colorectal cancer: a comprehensive systematic review of clinical presentation, cardiac involvement, and outcomes.Clinical & experimental metastasis · 2026Pooled it
- Cardiac Septal Metastasis From Poorly Differentiated Colorectal Adenocarcinoma: A Rare Case Illustrating the Role of Multimodal Imaging and Multidisciplinary Management.Case reports in cardiology · 2025Article
- Metastasis of colorectal adenocarcinoma to the right ventricle in a young man: a case report.The Pan African medical journal · 2023Article
- Intracardiac Metastasis of Colonic Adenocarcinoma 12 Years After Primary Tumor Control and Without Any Sign of Other Metastasis: A Case Report.Arquivos brasileiros de cardiologia · 2022Article
- A Rare Case of Cardiac Metastasis from Colon Cancer.Iranian journal of pathology · 2022Article
- Fruquintinib beneficial in elderly patient with neoplastic pericardial effusion from rectal cancer: A case report.World journal of clinical cases · 2021Article
- Metastatic colorectal carcinoma to the right atrium: a case report and review of the literature.Cardio-oncology (London, England) · 2021Article
- Capecitabine Plus Bevacizumab for Cardiac Metastasis of Sigmoid Colon Cancer: Case Report and Literature Review.In vivo (Athens, Greece)Review
- Large Metastatic Cardiac Tumor from Ascending Colon Cancer with Autopsy.Case reports in gastroenterologyArticle
- Solitary Cardiac Metastasis from Colorectal Cancer: A Case Report.Case reports in oncologyArticle
- Diagnostic and Therapeutic Challenges Associated with the Rare Cardiac Metastasis Complicating Rectal Adenocarcinoma.Case reports in oncologyArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
11 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundCardiac metastasis from colorectal cancer is rare. There is little evidence supporting the effectiveness of chemotherapy, and standard therapy for metastatic cardiac tumors has not been established. CASE PRESENTATION: A 76-year-old woman presented with a right ventricle tumor that was detected incidentally on screening cardiac ultrasonography. The initial computed tomography (CT) scan showed the cardiac tumor, which was approximately 40 mm in size, and multiple pulmonary nodules. Serum levels of tumor markers CEA and CA19-9 were elevated aberrantly. The suspected primary tumor, a well-differentiated adenocarcinoma of the transverse colon with wild-type KRAS was found by colonoscopy, and treatment with 5-fluorouracil, leucovorin, and oxaliplatin (modified FOLFOX6) plus panitumumab was initiated. After 4 courses of the therapy, a CT scan showed that the cardiac tumor size had markedly decreased and the pulmonary nodules had diminished. The serum levels of CEA and CA19-9 were also markedly decreased. After 12 courses of chemotherapy during 10 months of treatment, the patient continued to show a partial response, and she remained asymptomatic with continuation of the treatment through 15 courses.
conclusionTo the best of our knowledge, this is the first report of the efficacy of combination therapy using cytotoxic and molecular targeted agents against cardiac metastasis from colon cancer.
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