ArticleArchives of endocrinology and metabolism
Radiation exposure and thyroid cancer: a review.
Article in Archives of endocrinology and metabolism. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 104 papers, 5 of them syntheses that pooled it.
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Who cites it
104 citing papers in PubMed, 5 syntheses or guidelines pooled it.
- Predictors of thyroid cancer in paediatric patients with thyroid nodules: A systematic review and meta-analysis.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2026Pooled it
- Global multi-ancestry genome-wide analyses identify genes and biological pathways associated with thyroid cancer and benign thyroid diseases.Nature genetics · 2026Pooled it
- Familial Risk Factors in Thyroid Cancer Across Generations and Geographics: A Systematic Review and Meta-Analysis.Current oncology (Toronto, Ont.) · 2025Pooled it
- Global incidence and prevalence of differentiated thyroid cancer in childhood: systematic review and meta-analysis.Frontiers in endocrinology · 2023Pooled it
- A Meta-Analysis for Association of XRCC1, XRCC2 and XRCC3 Polymorphisms with Susceptibility to Thyroid Cancer.Asian Pacific journal of cancer prevention : APJCP · 2021Pooled it
- Subacute thyroid injury and relative parathyroid preservation following ionizing radiation: altered HSP-90 immunoexpression in a rat model.Journal of molecular histology · 2026Article
- [Prognostic research in endocrinology: design and common errors].Problemy endokrinologii · 2026Review
- Radiation Safety Knowledge, Perceptions, and Self-Reported Practices Among Healthcare Workers in Radiology and Nuclear Medicine: A Cross-Sectional Survey.Healthcare (Basel, Switzerland) · 2026Article
- Review
- Transradial versus transfemoral neuroangiography in a tertiary pediatric hospital-a propensity score matched study.European radiology · 2026Article
- The Thyroid Under Pressure: Heavy Metals, Endocrine Disruptors and Translational Insights into Carcinogenesis and Thyroid Dysfunctions.International journal of molecular sciences · 2026Review
- Occupational Variation in Thyroid Cancer Incidence in the Nordic Countries.Oncology and therapy · 2026Article
- Imaging Assessment and Management of Pediatric Thyroid Nodules: Emphasis on Application of 2021 K-TIRADS.Journal of the Korean Society of Radiology · 2026Review
- Integrative Single-Cell and Machine Learning Analysis Identifies an EMT-Associated Prognostic Signature for Papillary Thyroid Cancer.Cancer medicine · 2026Article
- Exploring the link between nitrate exposure and thyroid cancer: A nationwide state-level analysis.Journal of the Endocrine Society · 2026Article
- Thyroid cancer in Chinese military flight personnel: Characteristics and management advances.World journal of clinical oncology · 2026Review
- Machine-learning-based tumor segmentation and classification using dynamic optical contrast imaging for thyroid cancer.Biophotonics discovery · 2026Article
- Preemptive iodide treatment in the event of a nuclear disaster: The prepper's guide to the galaxy.Experimental physiology · 2025Article
- Progress in Drug-targeted Therapy for Papillary Thyroid Carcinoma.Current oncology reports · 2025Review
- Article
44 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The association between radiation exposure and the occurrence of thyroid cancer has been well documented, and the two main risk factors for the development of a thyroid cancer are the radiation dose delivered to the thyroid gland and the age at exposure. The risk increases after exposure to a mean dose of more than 0.05-0.1 Gy (50-100mGy). The risk is more important during childhood and decreases with increased age at exposure, being low in adults. After exposure, the minimum latency period before the appearance of thyroid cancers is 5 to 10 years. Papillary carcinoma (PTC) is the most frequent form of thyroid carcinoma diagnosed after radiation exposure, with a higher prevalence of the solid subtype in young children with a short latency period and of the classical subtype in cases with a longer latency period after exposure. Molecular alterations, including intra-chromosomal rearrangements, are frequently found. Among them, RET/PTC rearrangements are the most frequent. Current research is directed on the mechanism of genetic alterations induced by radiation and on a molecular signature that can identify the origin of thyroid carcinoma after a known or suspected exposure to radiation.
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