Evidence map›Paper›PMID 28225763›Full record

ArticleNature2017

Elucidation of the biosynthesis of the methane catalyst coenzyme F

Simon J Moore, Sven T Sowa, Christopher Schuchardt, Evelyne Deery, Andrew D Lawrence, José Vazquez Ramos, Susan Billig, Claudia Birkemeyer, Peter T Chivers, Mark J Howard and 3 more

Erratum issuedOpen access · greenAbstract read
In one paragraph

Article in Nature, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 52 papers.

0numbers the graph read from it
0cells of the map it votes in
52citing papers in PubMed
5.8field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

52 citing papers in PubMed, 128 citations in OpenAlex.

  1. Review
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  5. Article
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  11. On the Shoulders of Giants-Reaching for Nitrogenase.Molecules (Basel, Switzerland) · 2023
    Review
  12. Article
  13. Article
  14. Article
  15. Article
  16. Review
  17. Review
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

13 authors at 4 institutions in 2 countries.

Simon J MooreSchool of Biosciences, University of Kent, Giles Lane, Canterbury, Kent CT2 7NJ, UK.
Sven T SowaInstitute of Biochemistry, Leipzig University, Brüderstrasse 34, 04103 Leipzig, Germany.
Christopher SchuchardtInstitute of Biochemistry, Leipzig University, Brüderstrasse 34, 04103 Leipzig, Germany.
Evelyne DeerySchool of Biosciences, University of Kent, Giles Lane, Canterbury, Kent CT2 7NJ, UK.
Andrew D LawrenceSchool of Biosciences, University of Kent, Giles Lane, Canterbury, Kent CT2 7NJ, UK.
José Vazquez RamosInstitute of Biochemistry, Leipzig University, Brüderstrasse 34, 04103 Leipzig, Germany.
Susan BilligInstitute of Analytical Chemistry, Leipzig University, Linnéstrasse 3, 04103 Leipzig, Germany.
Claudia BirkemeyerInstitute of Analytical Chemistry, Leipzig University, Linnéstrasse 3, 04103 Leipzig, Germany.
Peter T ChiversDepartment of Chemistry and Department of Biosciences, Durham University, Durham DH1 3LE, UK.
Mark J HowardSchool of Biosciences, University of Kent, Giles Lane, Canterbury, Kent CT2 7NJ, UK.
Stephen E J RigbyManchester Institute of Biotechnology, School of Chemistry, University of Manchester, 131 Princess Street, Manchester M1 7DN, UK.
Gunhild LayerInstitute of Biochemistry, Leipzig University, Brüderstrasse 34, 04103 Leipzig, Germany.
Martin J WarrenSchool of Biosciences, University of Kent, Giles Lane, Canterbury, Kent CT2 7NJ, UK.
Leipzig University · DEUniversity of Kent · GBDurham University · GBUniversity of Manchester · GB

Funding

Biotechnology and Biological Sciences Research Council B19356/2Biotechnology and Biological Sciences Research Council BB/E013007/1
6 · The paper itself

Abstract

Methane biogenesis in methanogens is mediated by methyl-coenzyme M reductase, an enzyme that is also responsible for the utilization of methane through anaerobic methane oxidation. The enzyme uses an ancillary factor called coenzyme F

Indexed as

BiocatalysisBiosynthetic PathwaysAmidohydrolasesCoenzymesLyasesMetalloporphyrinsMethaneMethanosarcina barkeriMultigene FamilyNickelOxidoreductasesTetrapyrrolesUroporphyrinsAmidohydrolasesCoenzymesfactor F430LyasesMetalloporphyrinsMethanemethyl coenzyme M reductasemethyl radicalNickelOxidoreductasessirohydrochlorinTetrapyrrolesUroporphyrins

Identifiers

PMID28225763
PMCPMC5337119
OpenAlexW2589779285

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.