Evidence map›Paper›PMID 28225052›Full record

Trial reportEuropean journal of clinical nutrition2017

Building better bones in childhood: a randomized controlled study to test the efficacy of a dietary intervention program to increase calcium intake.

D R Weber, L J Stark, R F Ittenbach, V A Stallings, B S Zemel

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in European journal of clinical nutrition, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.1field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Dietary calcium intake recommendations for children: are they too high?The American journal of clinical nutrition · 2017
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

D R WeberUniversity of Rochester School of Medicine and Dentistry, Rochester NY, USA.
L J StarkCincinnati Children's Hospital Medical Center, Cincinnati, OH, USA.
R F IttenbachCincinnati Children's Hospital Medical Center, Cincinnati, OH, USA.
V A StallingsThe Children's Hospital of Philadelphia and Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, USA.
B S ZemelThe Children's Hospital of Philadelphia and Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, USA.
Children's Hospital of Philadelphia · USCincinnati Children's Hospital Medical Center · USUniversity of Rochester · US

Funding

Institutional Clinical and Translational Science AwardUL1TR000003 · NCATS · UNIVERSITY OF PENNSYLVANIA · PI FITZGERALD, GARRET A · 2012 to 2015
$38.9M
Career Development Program in Pediatric Diabetes Research (K12) at CHOPK12DK094723 · NIDDK · CHILDREN'S HOSP OF PHILADELPHIA · PI WILLI, STEVEN M · 2011 to 2020
$3.6M
Translational Molecular Pediatric ResearchK12HD068373 · NICHD · UNIVERSITY OF ROCHESTER · PI SCHOR, NINA F · 2011 to 2015
$2.0M
BUILDING BETTER BONES IN CHILDRENR01HD037748 · NICHD · CHILDREN'S HOSPITAL OF PHILADELPHIA · PI ZEMEL, BABETTE S · 1999 to 2003
$1.7M
NCATS NIH HHS UL1 TR000003NICHD NIH HHS K12 HD068373NICHD NIH HHS R01 HD037748NIDDK NIH HHS K12 DK094723
6 · The paper itself

Abstract

BACKGROUND/

objectivesMany children do not consume the recommended daily allowance of calcium. Inadequate calcium intake in childhood may limit bone accrual. The objective of this study was to determine if a behavioral modification and nutritional education (BM-NE) intervention improved dietary calcium intake and bone accrual in children. SUBJECTS/

methods139 (86 female) healthy children, 7-10 years of age, were enrolled in this randomized controlled trial conducted over 36 months. Participants randomized to the BM-NE intervention attended five sessions over a 6-week period designed to increase calcium intake to 1500 mg/day. Participants randomized to the usual care (UC) group received a single nutritional counseling session. The Calcium Counts Food Frequency Questionnaire was used to assess calcium intake; dual energy X-ray absorptiometry was used to assess areal bone mineral density (aBMD) and bone mineral content (BMC). Longitudinal mixed effects models were used to assess for an effect of the intervention on calcium intake, BMC and aBMD.

resultsBM-NE participants had greater increases in calcium intake that persisted for 12 months following the intervention compared with UC. The intervention had no effect on BMC or aBMD accrual. Secondary analyses found a negative association between calcium intake and adiposity such that greater calcium intake was associated with lesser gains in body mass index and fat mass index.

conclusionsA family-centered BM-NE intervention program in healthy children was successful in increasing calcium intake for up to 12 months but had no effect on bone accrual. A beneficial relationship between calcium intake and adiposity was observed and warrants future study.

Indexed as

Absorptiometry, PhotonBody Mass IndexBone and BonesBone DensityBone DevelopmentCalcium, DietaryChildChild DevelopmentFemaleFollow-Up StudiesHumansMaleCalcium, Dietary

Identifiers

PMID28225052
PMCPMC5462896
OpenAlexW2590023419

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.