Evidence map›Paper›PMID 28224344›Full record

ArticleJournal of autism and developmental disorders2017

Brief Report: Characteristics of preschool children with ASD vary by ascertainment.

Lori-Ann R Sacrey, Lonnie Zwaigenbaum, Peter Szatmari, Susan Bryson, Stelios Georgiades, Jessica Brian, Isabel M Smith, Tracy Vaillancourt, Nancy Garon, Caroline Roncadin and 1 more

Abstract readComparative Study
PubMed Publisher
In one paragraph

Article in Journal of autism and developmental disorders, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Review
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  5. Article
  6. Heterogeneity of autism symptoms in community-referred infants and toddlers at elevated or low familial likelihood of autism.Autism research : official journal of the International Society for Autism Research · 2023
    Article
  7. Article
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  10. Towards a Data-Driven Approach to Screen for Autism Risk at 12 Months of Age.Journal of the American Academy of Child and Adolescent Psychiatry · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Lori-Ann R SacreyDepartment of Pediatrics, University of Alberta, Edmonton, AB, Canada. sacrey@ualberta.ca.
Lonnie ZwaigenbaumDepartment of Pediatrics, University of Alberta, Edmonton, AB, Canada.
Peter SzatmariUniversity of Toronto, Toronto, ON, Canada.
Susan BrysonDalhousie University/IWK Health Centre, Halifax, NS, Canada.
Stelios GeorgiadesMcMaster Univeristy, Hamilton, ON, Canada.
Jessica BrianUniversity of Toronto, Toronto, ON, Canada.
Isabel M SmithDalhousie University/IWK Health Centre, Halifax, NS, Canada.
Tracy VaillancourtUniversity of Ottawa, Ottawa, ON, Canada.
Nancy GaronMount Allison University, Sackville, NB, Canada.
Caroline RoncadinUniversity of Toronto, Toronto, ON, Canada.
Mayada ElsabbaghMcGill University, Montreal, QC, Canada.

Funding

CIHR
6 · The paper itself

Abstract

Prospective studies of infant siblings of children diagnosed with autism spectrum disorder (ASD) provide a unique opportunity to characterize ASD as it unfolds. A critical question that remains unanswered is whether and how these children with ASD resemble other children identified from the community, including those with no family history. The purpose of this study was to compare clinical characteristics of children with ASD identified by each method (n = 86 per group), drawn from two Canadian longitudinal research cohorts. Children ascertained from a prospective cohort were less severely affected and included a larger proportion of girls, compared to the clinically referred sample. These results may have important implications for conclusions drawn from studies of high-risk and clinically referred cohorts.

Indexed as

Autism Spectrum DisorderCanadaChildChild, PreschoolFemaleHumansInfantLongitudinal StudiesMaleProspective StudiesSiblingsAutism spectrum disorderCommunity referralComparisonHigh-risk siblingsProspective

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.