Evidence map›Paper›PMID 28224307›Full record

ArticleSports medicine (Auckland, N.Z.)2017

Endocrinological Roles for Testosterone in Resistance Exercise Responses and Adaptations.

David R Hooper, William J Kraemer, Brian C Focht, Jeff S Volek, William H DuPont, Lydia K Caldwell, Carl M Maresh

Abstract read
PubMed Publisher
In one paragraph

Article in Sports medicine (Auckland, N.Z.), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
36citing papers in PubMed, 2 pooled it
3.7field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

36 citing papers in PubMed, 2 syntheses or guidelines pooled it, 77 citations in OpenAlex.

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  20. A botanical extract blend ofFrontiers in nutrition · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

David R HooperDepartment of Human Sciences, The Ohio State University, A054 PAES Building, 305 Annie and John Glenn Avenue, Columbus, OH, 43210, USA.
William J KraemerDepartment of Human Sciences, The Ohio State University, A054 PAES Building, 305 Annie and John Glenn Avenue, Columbus, OH, 43210, USA. kraemer.44@osu.edu.
Brian C FochtDepartment of Human Sciences, The Ohio State University, A054 PAES Building, 305 Annie and John Glenn Avenue, Columbus, OH, 43210, USA.
Jeff S VolekDepartment of Human Sciences, The Ohio State University, A054 PAES Building, 305 Annie and John Glenn Avenue, Columbus, OH, 43210, USA.
William H DuPontDepartment of Human Sciences, The Ohio State University, A054 PAES Building, 305 Annie and John Glenn Avenue, Columbus, OH, 43210, USA.
Lydia K CaldwellDepartment of Human Sciences, The Ohio State University, A054 PAES Building, 305 Annie and John Glenn Avenue, Columbus, OH, 43210, USA.
Carl M MareshDepartment of Human Sciences, The Ohio State University, A054 PAES Building, 305 Annie and John Glenn Avenue, Columbus, OH, 43210, USA.
The Ohio State University · USArmstrong Atlantic State University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Chronic increases in testosterone levels can significantly increase hypertrophy and strength, as has been demonstrated by pharmacological intervention. However, decreases in basal testosterone levels can have the opposite result, as has been seen in hypogonadal populations. Because of these profound effects on hypertrophy and strength, testosterone has often been studied in conjunction with resistance exercise to examine whether the endocrine system plays a role in adaptations to the stimulus. Whereas some studies have demonstrated a chronic increase in basal testosterone, others have failed to find an adaptation to regular resistance exercise. However, improvements in strength and hypertrophy appear to be possible regardless of the presence of this adaptation. Testosterone has also been shown to acutely rise immediately following an acute resistance exercise bout. While this substantial mobilization of testosterone is brief, its effects are seen for several hours through the upregulation of the androgen receptor. The role of this acute response at present is unknown, but further study of the non-genomic action and possible intracrinological processes is warranted. This response does not seem to be necessary for resistance training adaptations to occur either, but whether this response optimizes such adaptations has not yet been determined.

Indexed as

Adaptation, PhysiologicalResistance TrainingExerciseHumansMuscle, SkeletalMuscle StrengthTestosteroneTestosteroneDHEAResistance ExerciseResistance TrainingTestosteroneTestosterone Level

Identifiers

PMID28224307
OpenAlexW2591039580

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.