Evidence map›Paper›PMID 28224046›Full record

ArticleTremor and other hyperkinetic movements (New York, N.Y.)2017

Eighth International Chorea-Acanthocytosis Symposium: Summary of Workshop Discussion and Action Points.

Samuel S Pappas, Juan Bonifacino, Adrian Danek, William T Dauer, Mithu De, Lucia De Franceschi, Gilbert DiPaolo, Robert Fuller, Volker Haucke, Andreas Hermann and 11 more

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Tremor and other hyperkinetic movements (New York, N.Y.), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.7field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 4 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

21 authors at 9 institutions in 4 countries.

Samuel S PappasDepartment of Neurology, University of Michigan, Ann Arbor, MI, USA.
Juan BonifacinoCell Biology and Neurobiology Branch, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD, USA.
Adrian DanekNeurologische Klinik und Poliklinik, Ludwig-Maximilians-Universität, Munich, Germany.
William T DauerDepartment of Neurology, University of Michigan, Ann Arbor, MI, USA; Neurology Service, VAAAHS, University of Michigan, Ann Arbor, MI, USA; Udall Centre, University of Michigan, Ann Arbor, MI, USA; Department of Cell and Developmental Biology, University of Michigan, Ann Arbor, MI, USA.
Mithu DeDepartment of Biological Chemistry, University of Michigan, Ann Arbor, MI, USA.
Lucia De FranceschiDepartment of Medicine, University of Verona and Azienda Ospedaliera Universitaria Integrata, Verona, Italy.
Gilbert DiPaoloDenali Therapeutics, San Francisco, CA, USA.
Robert FullerDepartment of Biological Chemistry, University of Michigan, Ann Arbor, MI, USA.
Volker HauckeDepartment of Molecular Pharmacology and Cell Biology, Leibniz Institut für Molekulare Pharmakologie, Berlin, Germany.
Andreas HermannDepartment of Neurology, Technische Universität, Dresden, Germany; German Center for Neurodegenerative Diseases (DZNE), Dresden, Germany.
Benoit KornmannInstitute of Biochemistry, ETH, Zurich, Switzerland.
Bernhard LandwehrmeyerDepartment of Neurology, University of Ulm, Ulm, Germany.
Johannes LevinNeurologische Klinik und Poliklinik, Ludwig-Maximilians-Universität, Munich, Germany; German Center for Neurodegenerative Diseases (DZNE), Munich, Germany.
Aaron M NeimanDepartment of Biochemistry and Cell Biology, Stony Brook University, New York, NY, USA.
Dobrila D RudnickiDepartment of Psychiatry, Johns Hopkins University, Baltimore, MD, USA.
Ody SibonDepartment of Cell Biology, University Medical Center Groningen, University of Groningen, Gronigen, The Netherlands.
Antonio Velayos-BaezaThe Wellcome Trust Centre for Human Genetics, Oxford, UK.
Jan J VonkDepartment of Cell Biology, University Medical Center Groningen, University of Groningen, Gronigen, The Netherlands.
Ruth H WalkerDepartment of Neurology, James J. Peters VAMC, Bronx, NY, USA; Department of Neurology, Mount Sinai School of Medicine, New York, NY, USA.
Lois S WeismanDepartment of Cell and Developmental Biology, University of Michigan, Ann Arbor, MI, USA.
Roger L AlbinDepartment of Neurology, University of Michigan, Ann Arbor, MI, USA; Neurology Service, VAAAHS, University of Michigan, Ann Arbor, MI, USA; Udall Centre, University of Michigan, Ann Arbor, MI, USA; GRECC, VAAAHS, University of Michigan, Ann Arbor, MI, USA,; Michigan Alzheimer's Disease Center, University of Michigan, Ann Arbor, MI, USA.
University of Michigan–Ann Arbor · USCentre for Human Genetics · GBDenali Therapeutics (United States) · USETH Zurich · CHJohns Hopkins University · USLudwig-Maximilians-Universität München · DENational Institutes of Health · USStony Brook University · USUniversität Ulm · DE

Funding

Protein Trafficking In The Endosomal-Lysosomal SystemZIAHD001607 · NICHD · EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD HEALTH & HUMAN DEVELOPMENT · PI BONIFACINO, JUAN · 2009 to 2025
$48.3M
Equipment supplement for grant R01 GM072540 Assembly and Function of the Yeast Spore Wall.R01GM072540 · NIGMS · STATE UNIVERSITY NEW YORK STONY BROOK · PI NEIMAN, AARON M · 2005 to 2025
$7.1M
Roles and regulation of PI(3,5)P2 and PI5P in neuronsR01NS064015 · NINDS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI WEISMAN, LOIS S · 2009 to 2018
$3.8M
TorsinA function and dystonia-related dysfunction in developing and mature CNSR01NS077730 · NINDS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI DAUER, WILLIAM T. · 2013 to 2017
$1.9M
NIGMS NIH HHS R01 GM072540NINDS NIH HHS R01 NS064015NINDS NIH HHS R01 NS077730
6 · The paper itself

Abstract

Chorea-Acanthocytosis (ChAc) is a rare hereditary neurological disorder characterized by abnormal movements, red blood cell pathology, and progressive neurodegeneration. Little is understood of the pathogenesis of ChAc and related disorders (collectively Neuroacanthocytosis). The Eighth International Chorea-Acanthocytosis Symposium was held in May 2016 in Ann Arbor, MI, USA, and focused on molecular mechanisms driving ChAc pathophysiology. Accompanying the meeting, members of the neuroacanthocytosis research community and other invited scientists met in a workshop to discuss the current understanding and next steps needed to better understand ChAc pathogenesis. These discussions identified several broad and critical needs for advancing ChAc research and patient care, and led to the definition of 18 specific action points related to functional and molecular studies, animal models, and clinical research. These action points, described below, represent tractable research goals to pursue for the next several years.

Indexed as

Chorea AcanthocytosisChoreinNeuroacanthocytosisVPS13VPS13A

Identifiers

PMID28224046
PMCPMC5313633
OpenAlexW2592036044

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.