ReviewFrontiers in neurology2017
Molecular Mechanisms in Mood Regulation Involving the Circadian Clock.
Review in Frontiers in neurology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
30 citing papers in PubMed, 1 synthesis or guideline pooled it, 70 citations in OpenAlex.
- Parkinson's Disease is Associated with Dysregulations of a Dopamine-Modulated Gene Network Relevant to Sleep and Affective Neurobehaviors in the Striatum.Scientific reports · 2019Pooled it
- A Chrono-Metabolic Approach to Mental Health: Current Perspectives on Circadian Rhythms, Gut Microbiota, and Microbial Metabolites in Mood Disorders.Metabolites · 2026Review
- [KLF10 overexpression alleviates neuroinflammation and anxiety-depressive disorder in rats by downregulating the NF-κB/NLRP3 pathway].Nan fang yi ke da xue xue bao = Journal of Southern Medical University · 2026Article
- From Monoamines to Systems Psychiatry: Rewiring Depression Science and Care (1960s-2025).Biomedicines · 2025Article
- The Regulation of Catecholamine Biosynthesis by the Gas Transmitters Carbon Monoxide and Hydrogen Sulfide.Current issues in molecular biology · 2025Article
- Lack of Bmal1 leads to changes in rhythmicity and impairs motivation towards natural stimuli.Open biology · 2024Article
- Machine learning and expression analyses reveal circadian clock features predictive of anxiety.Scientific reports · 2022Article
- New Insights Into the Pivotal Role of CREB-Regulated Transcription Coactivator 1 in Depression and Comorbid Obesity.Frontiers in molecular neuroscience · 2022Review
- Machine Learning Analyses Reveal Circadian Features Predictive of Risk for Sleep Disturbance.Nature and science of sleep · 2022Article
- A mathematical model of circadian rhythms and dopamine.Theoretical biology & medical modelling · 2021Article
- The Combined Effects of Magnesium Oxide and Inulin on Intestinal Microbiota and Cecal Short-Chain Fatty Acids.Nutrients · 2021Article
- Traumatic stress and the circadian system: neurobiology, timing and treatment of posttraumatic chronodisruption.European journal of psychotraumatology · 2020Review
- Physiological and cognitive consequences of a daily 26 h photoperiod in a primateProceedings. Biological sciences · 2020Article
- Effect of Dose and Timing of Burdock (Microorganisms · 2020Article
- Regulation of Circadian Genes by the MAPK Pathway: Implications for Rapid Antidepressant Action.Neuroscience bulletin · 2020Review
- Understanding Quantitative Circadian Regulations Are Crucial Towards Advancing Chronotherapy.Cells · 2019Review
- Sleep and Circadian Medicine: Time of Day in the Neurologic Clinic.Neurologic clinics · 2019Review
- Working Time Society consensus statements: Evidence-based effects of shift work on physical and mental health.Industrial health · 2019Review
- Measuring Food Anticipation in Mice.Clocks & sleep · 2019Article
- REM sleep's unique associations with corticosterone regulation, apoptotic pathways, and behavior in chronic stress in mice.Proceedings of the National Academy of Sciences of the United States of America · 2019Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The circadian system coordinates activities and functions in cells and tissues in order to optimize body functions in anticipation to daily changes in the environment. Disruption of the circadian system, due to irregular lifestyle such as rotating shift work, frequent travel across time-zones, or chronic stress, is correlated with several diseases such as obesity, cancer, and neurological disorders. Molecular mechanisms linking the circadian clock with neurological functions have been uncovered suggesting that disruption of the clock may be critically involved in the development of mood disorders. In this mini-review, I will summarize molecular mechanisms in which clock components play a central role for mood regulation. Such mechanisms have been identified in the monoaminergic system, the HPA axis, and neurogenesis.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.