Evidence map›Paper›PMID 28223934›Full record

ArticleFrontiers in aging neuroscience2017

Plasma Cystatin C and High-Density Lipoprotein Are Important Biomarkers of Alzheimer's Disease and Vascular Dementia: A Cross-Sectional Study.

Rui Wang, Zhaoyu Chen, Yongmei Fu, Xiaobo Wei, Jinchi Liao, Xu Liu, Bingjun He, Yunqi Xu, Jing Zou, Xiaoyan Yang and 5 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in aging neuroscience, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed
5.0field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 50 citations in OpenAlex.

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  8. Investigating Biological Pathways Underpinning the Longitudinal Association Between Loneliness and Cognitive Impairment.The journals of gerontology. Series A, Biological sciences and medical sciences · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 5 institutions in 2 countries.

Rui WangDepartments of Neurology, The Third Affiliated Hospital of Sun Yat-Sen University Guangzhou, China.
Zhaoyu ChenDepartments of Neurology, The Third Affiliated Hospital of Sun Yat-Sen University Guangzhou, China.
Yongmei FuDepartments of Emergency, The Third Affiliated Hospital of Sun Yat-Sen University Guangzhou, China.
Xiaobo WeiDepartments of Neurology, The Third Affiliated Hospital of Sun Yat-Sen University Guangzhou, China.
Jinchi LiaoDepartments of Neurology, The Third Affiliated Hospital of Sun Yat-Sen University Guangzhou, China.
Xu LiuDepartments of Neurology, The Third Affiliated Hospital of Sun Yat-Sen University Guangzhou, China.
Bingjun HeDepartments of Radiology, The Third Affiliated Hospital of Sun Yat-Sen University Guangzhou, China.
Yunqi XuDepartment of Neurology, Nanfang Hospital, Southern Medical University Guangzhou, China.
Jing ZouDepartments of Neurology, The Third Affiliated Hospital of Sun Yat-Sen University Guangzhou, China.
Xiaoyan YangDepartments of Emergency, The Third Affiliated Hospital of Sun Yat-Sen University Guangzhou, China.
Ruihui WengDepartments of Neurology, The Third Affiliated Hospital of Sun Yat-Sen University Guangzhou, China.
Sheng TanDepartments of Neurology, Zhujiang Hospital, Southern Medical University Guangzhou, China.
Christopher McElroyDepartment of Pharmacology and Neuroscience, University of North Texas Health Science Center Fort Worth, TX, USA.
Kunlin JinDepartment of Pharmacology and Neuroscience, University of North Texas Health Science Center Fort Worth, TX, USA.
Qing WangDepartments of Neurology, The Third Affiliated Hospital of Sun Yat-Sen UniversityGuangzhou, China; Guangdong Province Key Laboratory of Brain Function and DiseaseGuangzhou, China.
Third Affiliated Hospital of Sun Yat-sen University · CNSun Yat-sen University · CNUniversity of North Texas · USNanfang Hospital · CNSouthern Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

HIGHLIGHTS: Plasma Cys C levels were higher in patients with AD/VaD than in healthy subjects.Plasma HDL levels were lower in patients with AD/VaD than in healthy subjects.Plasma Cys C levels were significantly correlated with dementia.The ROC curve for the combination of Cys C and HDL showed potential diagnostic value in distinguishing AD/VaD from healthy subjects.

Indexed as

Alzheimer’s diseasecystatin Cdementiahigh-density lipoproteinvascular dementia

Identifiers

PMID28223934
PMCPMC5294921
OpenAlexW2587302224

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.