ArticleFrontiers in neurorobotics2017
A Computational Model for Spatial Navigation Based on Reference Frames in the Hippocampus, Retrosplenial Cortex, and Posterior Parietal Cortex.
Article in Frontiers in neurorobotics, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
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Who cites it
20 citing papers in PubMed, 52 citations in OpenAlex.
- Resting after learning facilitates memory consolidation and reverses spatial reorientation impairments in female 3xTg-AD mice.Journal of Alzheimer's disease : JAD · 2026Article
- A Hippocampal-Parietal Network for Reference Frame Coordination.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025Article
- Allocentric and egocentric spatial representations coexist in rodent medial entorhinal cortex.Nature communications · 2025Article
- Role of Reference Frames for a Safe Human-Robot Interaction.Sensors (Basel, Switzerland) · 2023Article
- Linking global top-down views to first-person views in the brain.Proceedings of the National Academy of Sciences of the United States of America · 2022Article
- Redesigning navigational aids using virtual global landmarks to improve spatial knowledge retrieval.NPJ science of learning · 2022Article
- Using virtual global landmark to improve incidental spatial learning.Scientific reports · 2022Article
- Scalp recorded theta activity is modulated by reward, direction, and speed during virtual navigation in freely moving humans.Scientific reports · 2022Article
- Tau Pathology Profile Across a Parietal-Hippocampal Brain Network Is Associated With Spatial Reorientation Learning and Memory Performance in the 3xTg-AD Mouse.Frontiers in aging · 2021Article
- Impaired Hippocampal-Cortical Interactions during Sleep in a Mouse Model of Alzheimer's Disease.Current biology : CB · 2020Article
- Neural Modulation of the Primary Auditory Cortex by Intracortical Microstimulation with a Bio-Inspired Electronic System.Bioengineering (Basel, Switzerland) · 2020Article
- The Neuroscience of Spatial Navigation and the Relationship to Artificial Intelligence.Frontiers in computational neuroscience · 2020Review
- Cerebral Hemodynamic Responses to the Sensory Conflict Between Visual and Rotary Vestibular Stimuli: An Analysis With a Multichannel Near-Infrared Spectroscopy (NIRS) System.Frontiers in human neuroscience · 2020Article
- Impaired Spatial Reorientation in the 3xTg-AD Mouse Model of Alzheimer's Disease.Scientific reports · 2019Article
- Functional Source Separation for EEG-fMRI Fusion: Application to Steady-State Visual Evoked Potentials.Frontiers in neurorobotics · 2019Article
- The retrosplenial-parietal network and reference frame coordination for spatial navigation.Behavioral neuroscience · 2018Review
- Cholinergic modulation of spatial learning, memory and navigation.The European journal of neuroscience · 2018Review
- Neural mechanisms of navigation involving interactions of cortical and subcortical structures.Journal of neurophysiology · 2018Review
- Flexible egocentric and allocentric representations of heading signals in parietal cortex.Proceedings of the National Academy of Sciences of the United States of America · 2018Article
- How to Characterize the Function of a Brain Region.Trends in cognitive sciences · 2018Review
Corrections and comments
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Authors and funding
3 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Behavioral studies for humans, monkeys, and rats have shown that, while traversing an environment, these mammals tend to use different frames of reference and frequently switch between them. These frames represent allocentric, egocentric, or route-centric views of the environment. However, combinations of either of them are often deployed. Neurophysiological studies on rats have indicated that the hippocampus, the retrosplenial cortex, and the posterior parietal cortex contribute to the formation of these frames and mediate the transformation between those. In this paper, we construct a computational model of the posterior parietal cortex and the retrosplenial cortex for spatial navigation. We demonstrate how the transformation of reference frames could be realized in the brain and suggest how different brain areas might use these reference frames to form navigational strategies and predict under what conditions an animal might use a specific type of reference frame. Our simulated navigation experiments demonstrate that the model's results closely resemble behavioral findings in humans and rats. These results suggest that navigation strategies may depend on the animal's reliance in a particular reference frame and shows how low confidence in a reference frame can lead to fluid adaptation and deployment of alternative navigation strategies. Because of its flexibility, our biologically inspired navigation system may be applied to autonomous robots.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.