Evidence map›Paper›PMID 28223917›Full record

ArticleFrontiers in molecular neuroscience2017

Gene Expression Profiling in the Injured Spinal Cord of

Adrián Valentin-Kahan, Gabriela B García-Tejedor, Carlos Robello, Omar Trujillo-Cenóz, Raúl E Russo, Fernando Alvarez-Valin

Abstract read
In one paragraph

Article in Frontiers in molecular neuroscience, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Adrián Valentin-KahanDepartment of Cellular and Molecular Neurophysiology, Instituto de Investigaciones Biológicas Clemente Estable Montevideo, Uruguay.
Gabriela B García-TejedorDepartment of Cellular and Molecular Neurophysiology, Instituto de Investigaciones Biológicas Clemente Estable Montevideo, Uruguay.
Carlos RobelloMolecular Biology Unit, Institut Pasteur de MontevideoMontevideo, Uruguay; Departamento de Bioquímica, Facultad de Medicina, Universidad de la RepublicaMontevideo, Uruguay.
Omar Trujillo-CenózDepartment of Cellular and Molecular Neurophysiology, Instituto de Investigaciones Biológicas Clemente Estable Montevideo, Uruguay.
Raúl E RussoDepartment of Cellular and Molecular Neurophysiology, Instituto de Investigaciones Biológicas Clemente Estable Montevideo, Uruguay.
Fernando Alvarez-ValinSección Biomatemática, Unidad de Genómica Evolutiva, Facultad de Ciencias, Universidad de la República Montevideo, Uruguay.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Slider turtles are the only known amniotes with self-repair mechanisms of the spinal cord that lead to substantial functional recovery. Their strategic phylogenetic position makes them a relevant model to investigate the peculiar genetic programs that allow anatomical reconnection in some vertebrate groups but are absent in others. Here, we analyze the gene expression profile of the response to spinal cord injury (SCI) in the turtle

Indexed as

amniotesanimal modelsaxon regenerationgenomicsglial scarringRNAseq analysisspinal cord injuriesturtles

Identifiers

PMID28223917
PMCPMC5293771

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.