Evidence map›Paper›PMID 28223804›Full record

ArticleInternational journal of nanomedicine2017

Decreased bacterial growth on titanium nanoscale topographies created by ion beam assisted evaporation.

Michelle Stolzoff, Jason E Burns, Arash Aslani, Eric J Tobin, Congtin Nguyen, Nicholas De La Torre, Negar H Golshan, Katherine S Ziemer, Thomas J Webster

Abstract read
In one paragraph

Article in International journal of nanomedicine, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Michelle StolzoffDepartment of Bioengineering, Northeastern University, Boston.
Jason E BurnsN2 Biomedical, Bedford, MA.
Arash AslaniN2 Biomedical, Bedford, MA.
Eric J TobinN2 Biomedical, Bedford, MA.
Congtin NguyenDepartment of Bioengineering, Northeastern University, Boston.
Nicholas De La TorreDepartment of Chemical Engineering, Northeastern University, Boston, MA, USA.
Negar H GolshanDepartment of Chemical Engineering, Northeastern University, Boston, MA, USA.
Katherine S ZiemerDepartment of Chemical Engineering, Northeastern University, Boston, MA, USA.
Thomas J WebsterDepartment of Bioengineering, Northeastern University, Boston; Department of Chemical Engineering, Northeastern University, Boston, MA, USA; Center of Excellence for Advanced Materials Research, University of King Abdulaziz, Jeddah, Saudi Arabia.

Funding

Long-term Prevention of Peri-Implantitis via Nano-textured, TiO/Ag SurfacesR43DE025526 · NIDCR · N2 BIOMEDICAL, LLC · PI BURNS, JASON E · 2015 to 2015
$225k
NIDCR NIH HHS R43 DE025526
6 · The paper itself

Abstract

Titanium is one of the most widely used materials for orthopedic implants, yet it has exhibited significant complications in the short and long term, largely resulting from poor cell-material interactions. Among these many modes of failure, bacterial infection at the site of implantation has become a greater concern with the rise of antibiotic-resistant bacteria. Nanostructured surfaces have been found to prevent bacterial colonization on many surfaces, including nanotextured titanium. In many cases, specific nanoscale roughness values and resulting surface energies have been considered to be "bactericidal"; here, we explore the use of ion beam evaporation as a novel technique to create nanoscale topographical features that can reduce bacterial density. Specifically, we investigated the relationship between the roughness and titanium nanofeature shapes and sizes, in which smaller, more regularly spaced nanofeatures (specifically 40-50 nm tall peaks spaced ~0.25 μm apart) were found to have more effect than surfaces with high roughness values alone.

Indexed as

Bacterial AdhesionCell ProliferationCells, CulturedHumansMicroscopy, Electron, ScanningNanostructuresOsteoblastsPhotoelectron SpectroscopyProstheses and ImplantsStaphylococcus aureusSurface PropertiesTitaniumTitaniumbacteriabone ingrowthIBADnanostructuressurface roughnesstitanium

Identifiers

PMID28223804
PMCPMC5310640

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.