ArticleClinical interventions in aging2017
Comparing the predictive accuracy of frailty, comorbidity, and disability for mortality: a 1-year follow-up in patients hospitalized in geriatric wards.
Article in Clinical interventions in aging, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 44 papers, 1 of them a synthesis that pooled it.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
44 citing papers in PubMed, 1 synthesis or guideline pooled it, 115 citations in OpenAlex.
- The Association Between the Clinical Frailty Scale and Adverse Health Outcomes in Older Adults in Acute Clinical Settings - A Systematic Review of the Literature.Clinical interventions in aging · 2023Pooled it
- Randomized phase 2b dose-escalation trial of stem cell therapy with laromestrocel for aging frailty.Cell stem cell · 2026Trial
- Cost of hospital care for the older adults according to their level of frailty. A cohort study in the Lazio region, Italy.PloS one · 2019Trial
- Effect of 6-month community-based exercise interventions on gait and functional fitness of an older population: a quasi-experimental study.Clinical interventions in aging · 2018Trial
- Allogeneic Mesenchymal Stem Cells Ameliorate Aging Frailty: A Phase II Randomized, Double-Blind, Placebo-Controlled Clinical Trial.The journals of gerontology. Series A, Biological sciences and medical sciences · 2017Trial
- Interactions between patterns of multimorbidity and functional status among hospitalized older patients: a novel approach using cluster analysis and association rule mining.Journal of translational medicine · 2024Article
- Factors associated with delirium in a real-world acute-care setting: analysis considering the interdependence of clinical variables with the frailty syndrome.European geriatric medicine · 2024Article
- Pre-Therapeutic Assessment of Older People in Sub-Saharan Africa: Introduction to the Comprehensive Geriatric Assessment.Journal of clinical medicine · 2024Review
- Management of Vertebral Fragility Fracture in Older People: Recommendations from a Spanish Consensus of Experts.Geriatrics (Basel, Switzerland) · 2024Article
- Which comorbidity index is more appropriate for geriatric patients from the frailty perspective?European geriatric medicine · 2024Article
- Use of frailty assessment instruments in nephrology populations: a scoping review.BMC geriatrics · 2023Article
- Accumulation of Chronic Disease Among Survivors of Childhood Cancer Predicts Early Mortality.Journal of clinical oncology : official journal of the American Society of Clinical Oncology · 2023Article
- Comparison of two different frailty scales in the longitudinal Swedish Adoption/Twin Study of Aging (SATSA).Scandinavian journal of public health · 2023Article
- Feasibility of a 12-Month Follow-Up in Swiss Older Adults after Post-Acute Care in Nursing Homes-A Pilot Study.Geriatrics (Basel, Switzerland) · 2023Article
- Medium and long-term prognosis in hospitalised older adults with multimorbidity. A prospective cohort study.PloS one · 2023Article
- Accelerated aging in people experiencing homelessness: A rapid review of frailty prevalence and determinants.Frontiers in public health · 2023Review
- Frailty modifies the effect of polypharmacy and multimorbidity on the risk of death among nursing home residents: Results from the SHELTER study.Frontiers in medicine · 2023Article
- Pathophysiology and Management of Heart Failure in the Elderly.The International journal of angiology : official publication of the International College of Angiology, Inc · 2022Article
- Impact of a multidisciplinary nutritional support team on quality improvement for patients receiving home parenteral nutrition.BMJ nutrition, prevention & health · 2022Article
- Age Increases the Risk of Mortality by Four-Fold in Patients with Emergent Paralytic Ileus: Hospital Length of Stay, Sex, Frailty, and Time to Operation as Other Risk Factors.International journal of environmental research and public health · 2022Article
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundStudies evaluating and comparing the power of frailty, comorbidity, and disability instruments, together and in parallel, for predicting mortality are limited.
objectiveThis study aimed to evaluate and compare the measures of frailty, comorbidity, and disability in predicting 1-year mortality in geriatric inpatients.
designProspective cohort study. PATIENTS AND
settingA total of 307 inpatients aged ≥65 years in geriatric wards of a general hospital participated in the study. MEASUREMENTS: The patients were evaluated in relation to different frailty, comorbidity, and disability instruments during their hospital stays. These included three frailty (the seven-category Clinical Frailty Scale [CFS-7], a 41-item frailty index [FI], and the FRAIL scale), two comorbidity (the Cumulative Illness Rating Scale for Geriatrics [CIRS-G] and the comorbidity domain of the FI [Comorbidity-D-FI]), and two disability instruments (disability in basic activities of daily living [ADL-Katz] and the instrumental and basic activities of daily living domains of the FI [IADL/ADL-D-FI]). The patients were followed-up over 1 year.
resultsUsing FI, CIRS-G, Comorbidity-D-FI, and ADL-Katz, this study identified a patient group with a high (≥50%) 1-year mortality rate in all of the patients and the two patient subgroups (ie, patients aged 65-82 years and ≥83 years). The CFS-7, FI, FRAIL scale, CIRS-G, Comorbidity-D-FI, and IADL/ADL-D-FI (analyzed as full scales) revealed useful discriminative accuracy for 1-year mortality (ie, an area under the curve >0.7) in all the patients and the two patient subgroups (all
conclusionAll the different instruments emerged as suitable tools for risk stratification in geriatric inpatients. Among them, CFS-7, and in those patients aged ≥83 years, also the FI, might most accurately predict 1-year mortality in the aforementioned group of individuals.
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