ArticleProceedings of the National Academy of Sciences of the United States of America2017
Designing allostery-inspired response in mechanical networks.
Article in Proceedings of the National Academy of Sciences of the United States of America, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 56 papers.
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Who cites it
56 citing papers in PubMed.
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- Autonomous codesign and fabrication of multistimuli-responsive material systems.Science advances · 2025Article
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- Soft Modes as a Predictive Framework for Low Dimensional Biological Systems across Scales.ArXiv · 2024Article
- Shortcuts to flexible structures.Proceedings of the National Academy of Sciences of the United States of America · 2024Article
- Topological mechanics without the topology: A universal, model-free approach to mechanical response.Proceedings of the National Academy of Sciences of the United States of America · 2024Article
- Adaptive nonequilibrium design of actin-based metamaterials: Fundamental and practical limits of control.Proceedings of the National Academy of Sciences of the United States of America · 2024Article
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- Learning to learn by using nonequilibrium training protocols for adaptable materials.Proceedings of the National Academy of Sciences of the United States of America · 2023Article
- Systematic modification of functionality in disordered elastic networks through free energy surface tailoring.Science advances · 2023Article
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Authors and funding
6 authors.
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Abstract
Recent advances in designing metamaterials have demonstrated that global mechanical properties of disordered spring networks can be tuned by selectively modifying only a small subset of bonds. Here, using a computationally efficient approach, we extend this idea to tune more general properties of networks. With nearly complete success, we are able to produce a strain between any two target nodes in a network in response to an applied source strain on any other pair of nodes by removing only ∼1% of the bonds. We are also able to control multiple pairs of target nodes, each with a different individual response, from a single source, and to tune multiple independent source/target responses simultaneously into a network. We have fabricated physical networks in macroscopic 2D and 3D systems that exhibit these responses. This work is inspired by the long-range coupled conformational changes that constitute allosteric function in proteins. The fact that allostery is a common means for regulation in biological molecules suggests that it is a relatively easy property to develop through evolution. In analogy, our results show that long-range coupled mechanical responses are similarly easy to achieve in disordered networks.
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