Evidence map›Paper›PMID 28223514›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2017

Selective autophagy limits cauliflower mosaic virus infection by NBR1-mediated targeting of viral capsid protein and particles.

Anders Hafrén, Jean-Luc Macia, Andrew J Love, Joel J Milner, Martin Drucker, Daniel Hofius

Open access · bronzeAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 154 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
154citing papers in PubMed, 1 pooled it
21.7field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

154 citing papers in PubMed, 1 synthesis or guideline pooled it, 276 citations in OpenAlex.

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  18. Biomolecular condensation of ERC1 recruits ATG8 and NBR1 to drive autophagosome formation for plant heat tolerance.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  19. G-Box Factors 14-3-3 Proteins Negatively RegulatePlants (Basel, Switzerland) · 2025
    Article
  20. Article

94 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 3 countries.

Anders HafrénDepartment of Plant Biology, Uppsala BioCenter, Swedish University of Agricultural Sciences (SLU), 75007 Uppsala, Sweden.
Jean-Luc MaciaNational Institute for Agricultural Research (INRA), UMR 385 Biology and Genetics of Plant-Pathogen Interactions, Campus International de Baillarguet, 34398 Montpellier Cedex 5, France.
Andrew J LoveCell and Molecular Sciences, The James Hutton Institute, Dundee DD2 5DA, United Kingdom.
Joel J MilnerPlant Science Group, School of Life Sciences, College of Medical Veterinary and Life Sciences, University of Glasgow, Glasgow G12 8QQ, United Kingdom.
Martin DruckerNational Institute for Agricultural Research (INRA), UMR 385 Biology and Genetics of Plant-Pathogen Interactions, Campus International de Baillarguet, 34398 Montpellier Cedex 5, France.
Daniel HofiusDepartment of Plant Biology, Uppsala BioCenter, Swedish University of Agricultural Sciences (SLU), 75007 Uppsala, Sweden; daniel.hofius@slu.se.
Biologie et Génétique des Interactions Plante-Parasite · FRSwedish University of Agricultural Sciences · SEJames Hutton Institute · GBUniversity of Glasgow · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Autophagy plays a paramount role in mammalian antiviral immunity including direct targeting of viruses and their individual components, and many viruses have evolved measures to antagonize or even exploit autophagy mechanisms for the benefit of infection. In plants, however, the functions of autophagy in host immunity and viral pathogenesis are poorly understood. In this study, we have identified both anti- and proviral roles of autophagy in the compatible interaction of cauliflower mosaic virus (CaMV), a double-stranded DNA pararetrovirus, with the model plant

Indexed as

Gene Expression Regulation, PlantAnimalsAphidsArabidopsisArabidopsis ProteinsAutophagyCapsidCapsid ProteinsCarrier ProteinsCaulimovirusHost-Pathogen InteractionsPlant DiseasesPlant ImmunityProteolysisSignal TransductionVirionArabidopsis ProteinsCapsid ProteinsCarrier ProteinsNBR1 protein, Arabidopsiscauliflower mosaic virusinnate immunityplant virusselective autophagyxenophagy

Identifiers

PMID28223514
PMCPMC5347569
OpenAlexW2590407045

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.