Evidence map›Paper›PMID 28223493›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2017

Crystal structure of

Elizabeth A Campbell, Shreya Kamath, Kanagalaghatta R Rajashankar, Mengyu Wu, Seth A Darst

Abstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

  1. Real-time capture of σNature communications · 2025
    Article
  2. Article
  3. Article
  4. Article
  5. A general mechanism for transcription bubble nucleation in bacteria.Proceedings of the National Academy of Sciences of the United States of America · 2023
    Article
  6. Article
  7. Article
  8. The Regulatory Functions of σInternational journal of molecular sciences · 2021
    Review
  9. Article
  10. Review
  11. Article
  12. Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Elizabeth A CampbellLaboratory for Molecular Biophysics, The Rockefeller University, New York, NY 10065.
Shreya KamathLaboratory for Molecular Biophysics, The Rockefeller University, New York, NY 10065.
Kanagalaghatta R RajashankarNortheastern Collaborative Access Team and Department of Chemistry and Chemical Biology, Cornell University, Argonne National Laboratory, Argonne, IL 60439.
Mengyu WuLaboratory for Molecular Biophysics, The Rockefeller University, New York, NY 10065.
Seth A DarstLaboratory for Molecular Biophysics, The Rockefeller University, New York, NY 10065; darst@rockefeller.edu.ORCID 0000-0002-8241-3153

Funding

Overall EvaluationP41GM103403 · NIGMS · CORNELL UNIVERSITY · PI EALICK, STEVEN E · 2012 to 2017
$14.3M
Structure, function, and regulation of the bacterial transcription cycleR35GM118130 · NIGMS · ROCKEFELLER UNIVERSITY · PI DARST, SETH A. · 2016 to 2025
$8.9M
Case Center for Synchrotron BiosciencesP30EB009998 · NIBIB · CASE WESTERN RESERVE UNIVERSITY · PI CHANCE, MARK R · 2009 to 2018
$8.4M
NIBIB NIH HHS P30 EB009998NIGMS NIH HHS P41 GM103403NIGMS NIH HHS R35 GM118130
6 · The paper itself

Abstract

The bacterial σ factors confer promoter specificity to the RNA polymerase (RNAP). One alternative σ factor, σ

Indexed as

BacteriaCrystallography, X-RayDNA-Binding ProteinsDNA-Directed RNA PolymerasesHoloenzymesPromoter Regions, GeneticSigma FactorTranscriptional ActivationTranscription, GeneticDNA-Binding ProteinsDNA-Directed RNA PolymerasesHoloenzymesSigma FactorRNA polymerasetranscriptionX-ray crystallographyσ54σN

Identifiers

PMID28223493
PMCPMC5347599

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.