Evidence map›Paper›PMID 28223399›Full record

ArticleGenome research2017

Centromere location in

Shamoni Maheshwari, Takayoshi Ishii, C Titus Brown, Andreas Houben, Luca Comai

Open access · bronzeAbstract read
In one paragraph

Article in Genome research, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 43 papers.

0numbers the graph read from it
0cells of the map it votes in
43citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

43 citing papers in PubMed, 79 citations in OpenAlex.

  1. Article
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  8. Pioneers of chromosome elimination.Frontiers in epigenetics and epigenomics · 2025
    Article
  9. Review
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  12. Review
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  18. Accelerated Breeding forPlants (Basel, Switzerland) · 2023
    Review
  19. The nature and organization of satellite DNAs inFrontiers in plant science · 2023
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Shamoni MaheshwariPlant Biology Department and Genome Center, University of California, Davis, California 95616, USA.ORCID 0000-0002-2880-7805
Takayoshi IshiiLeibniz Institute of Plant Genetics and Crop Plant Research (IPK) Gatersleben, 06466 Stadt Seeland, Germany.ORCID 0000-0001-6370-3289
C Titus BrownDepartment of Population Health and Reproduction, University of California, Davis, California 95616, USA.ORCID 0000-0001-6001-2677
Andreas HoubenLeibniz Institute of Plant Genetics and Crop Plant Research (IPK) Gatersleben, 06466 Stadt Seeland, Germany.ORCID 0000-0003-3419-239X
Luca ComaiPlant Biology Department and Genome Center, University of California, Davis, California 95616, USA.ORCID 0000-0003-2642-6619
University of California, Davis · USLeibniz-Institut für Pflanzengenetik und Kulturpflanzenforschung (IPK) · DE

Funding

Howard Hughes Medical Institute
6 · The paper itself

Abstract

During cell division, spindle fibers attach to chromosomes at centromeres. The DNA sequence at regional centromeres is fast evolving with no conserved genetic signature for centromere identity. Instead CENH3, a centromere-specific histone H3 variant, is the epigenetic signature that specifies centromere location across both plant and animal kingdoms. Paradoxically, CENH3 is also adaptively evolving. An ongoing question is whether CENH3 evolution is driven by a functional relationship with the underlying DNA sequence. Here, we demonstrate that despite extensive protein sequence divergence, CENH3 histones from distant species assemble centromeres on the same underlying DNA sequence. We first characterized the organization and diversity of centromere repeats in wild-type

Indexed as

Polymorphism, GeneticArabidopsisArabidopsis ProteinsCentromereCentromere Protein AEvolution, MolecularNucleosomesArabidopsis ProteinsCentromere Protein ANucleosomes

Identifiers

PMID28223399
PMCPMC5340974
OpenAlexW2591307260

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.