ReviewEuropean respiratory review : an official journal of the European Respiratory Society2017
Exertional dyspnoea in interstitial lung diseases: the clinical utility of cardiopulmonary exercise testing.
Review in European respiratory review : an official journal of the European Respiratory Society, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07315425 (Investigation of the Acute Effects of Blood Flow Restriction Aerobic Exercise on Hemodynamic Responses and Muscle Oxygen in Patients With Interstitial Lung Disease), which is not on this map. Cited by 31 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Investigation of the Acute Effects of Blood Flow Restriction Aerobic Exercise on Hemodynamic Responses and Muscle Oxygen in Patients With Interstitial Lung Disease
Who cites it
31 citing papers in PubMed, 2 syntheses or guidelines pooled it, 69 citations in OpenAlex.
- Utilisation of cardiopulmonary exercise testing for tailored pulmonary rehabilitation in people with interstitial lung diseases: A systematic review.Clinical rehabilitation · 2026Pooled it
- Clinically important changes and adverse events with centre-based or home-based pulmonary rehabilitation in chronic respiratory disease: A systematic review and meta-analysis.Chronic respiratory diseasePooled it
- Impact of high-flow oxygen therapy during exercise in idiopathic pulmonary fibrosis: a pilot crossover clinical trial.BMC pulmonary medicine · 2021Trial
- Effects of walking with a portable oxygen concentrator on muscle oxygenation while performing normal or pursed-lip breathing in patients with interstitial lung disease: a randomized crossover trial.Therapeutic advances in respiratory diseaseTrial
- Diaphragm excursion and peak oxygen uptake in fibrotic interstitial lung diseases.ERJ open research · 2026Article
- The TUG-10 test detects exertional desaturation in patients with interstitial lung disease: correlation with 6-minute-walk-test, cardiopulmonary exercise test, and lung diffusion capacity.European journal of applied physiology · 2026Article
- Aspects of Quality of Life in Interstitial Lung Disease: Pilot Observational Cross-Sectional Study in a Single Center.JMIR formative research · 2026Observational
- Cognitive impairment, depression, anxiety, and health-related quality of life in fibrotic ILD: a cross-sectional study.BMC pulmonary medicine · 2026Article
- When to Best Assess Breathlessness Abnormality During Incremental Cardiopulmonary Cycle Exercise Testing.Chest · 2026Article
- Mechanisms of exercise limitation and prevalence of pulmonary hypertension in hypersensitivity pneumonitis.ERJ open research · 2026Article
- The risk of symptomatic radiation pneumonitis in small cell lung cancer patients following sequential immunochemotherapy and radiotherapy: a multicenter retrospective cohort study.Radiation oncology (London, England) · 2025Article
- Pathophysiological Insights and Clinical Management Strategies for Interstitial Lung Diseases.Biomolecules & therapeutics · 2025Review
- Article
- Comparison of Six-minute Walk Test Parameters by Severity of Idiopathic and Non-idiopathic Pulmonary Fibrosis.Physical therapy research · 2025Article
- Exploring the potential of cardiopulmonary exercise testing (CPET) for tailored pulmonary rehabilitation in people with interstitial lung disease (ILD): A systematic review protocol.NIHR open research · 2024Article
- Normative Reference Equations for Breathlessness Intensity during Incremental Cardiopulmonary Cycle Exercise Testing.Annals of the American Thoracic Society · 2024Article
- The modified Medical Research Council scale misclassifies exertional breathlessness among people referred for exercise testing.ERJ open research · 2023Article
- The interplay of physical and cognitive function in rehabilitation of interstitial lung disease patients: a narrative review.Journal of thoracic disease · 2023Review
- Validity and repeatability of cardiopulmonary exercise testing in interstitial lung disease.BMC pulmonary medicine · 2022Article
- Comparison of heart rates at fixed percentages and the ventilatory thresholds in patients with interstitial lung disease.Scandinavian journal of medicine & science in sports · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Interstitial lung diseases (ILDs) represent a heterogeneous group of pathologies characterised by alveolar and interstitial damage, pulmonary inflammation (usually associated with fibrosis), decreased lung function and impaired gas exchange, which can be attributed to either a known or an unknown aetiology. Dyspnoea is one of the most common and disabling symptoms in patients with ILD, significantly impacting quality of life. The mechanisms causing dyspnoea are complex and not yet fully understood. However, it is recognised that dyspnoea occurs when there is an imbalance between the central respiratory efferent drive and the response of the respiratory musculature. The respiratory derangement observed in ILD patients at rest is even more evident during exercise. Pathophysiological mechanisms responsible for exertional dyspnoea and reduced exercise tolerance include altered respiratory mechanics, impaired gas exchange, cardiovascular abnormalities and peripheral muscle dysfunction.This review describes the respiratory physiology of ILD, both at rest and during exercise, and aims to provide comprehensive and updated evidence on the clinical utility of the cardiopulmonary exercise test in the assessment and management of these pathological entities. In addition, the role of exercise training and pulmonary rehabilitation programmes in the ILD population is addressed.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.