Evidence map›Paper›PMID 28223395›Full record

SynthesisEuropean respiratory review : an official journal of the European Respiratory Society2017

Oxygen therapy for interstitial lung disease: a systematic review.

Emily C Bell, Narelle S Cox, Nicole Goh, Ian Glaspole, Glen P Westall, Alice Watson, Anne E Holland

Registry-linked trialOpen access · diamondAbstract readMeta-AnalysisSystematic Review
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in European respiratory review : an official journal of the European Respiratory Society, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07512687 (Impact of Ambulatory Oxygen Delivery on Real-world Activity and Quality-of-life in Patients With Interstitial Lung Disease), which is not on this map. Cited by 73 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
73citing papers in PubMed, 2 pooled it
14.1field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07512687 narecruitingnot on this mapstarted 2026, after this paper: background citation

Impact of Ambulatory Oxygen Delivery on Real-world Activity and Quality-of-life in Patients With Interstitial Lung Disease (ILD) and Chronic Obstructive Pulmonary Disease (COPD)

TypeinterventionalSponsorState University of New York at BuffaloRan2026 to 2027Enrolled24ConditionsInterstitial Lung Disease, Chronic Obstructive Pulmonary Disease, HypoxemiaArmsPortable Oxygen Concentrator, Portable compressed oxygen D-tanks, No ambulatory oxygen therapy
3 · Its place in the literature

Who cites it

73 citing papers in PubMed, 2 syntheses or guidelines pooled it, 173 citations in OpenAlex.

  1. Supplemental oxygen for symptomatic relief in people with serious respiratory illness: a systematic review and meta-analysis.European respiratory review : an official journal of the European Respiratory Society · 2025
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13 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Emily C BellDept of Physiotherapy, Monash University, Clayton, Australia.
Narelle S CoxDept of Physiotherapy, Monash University, Clayton, Australia.
Nicole GohInstitute for Breathing and Sleep, Melbourne, Australia.
Ian GlaspoleGeneral Respiratory and Transplant, Alfred Health, Melbourne, Australia.
Glen P WestallGeneral Respiratory and Transplant, Alfred Health, Melbourne, Australia.
Alice WatsonDept of Physiotherapy, La Trobe University, Melbourne, Australia.
Anne E HollandDept of Physiotherapy, La Trobe University, Melbourne, Australia a.holland@alfred.org.au.
La Trobe University · AUMonash University · AUAustin Health · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This review aims to establish the impact of oxygen therapy on dyspnoea, health-related quality of life (HRQoL), exercise capacity and mortality in interstitial lung disease (ILD).We included studies that compared oxygen therapy to no oxygen therapy in adults with ILD. No limitations were placed on study design or intervention type. Two reviewers independently evaluated studies for inclusion, assessed risk of bias and extracted data. The primary outcome was dyspnoea.Eight studies evaluated the acute effects of oxygen (n=1509). There was no effect of oxygen therapy on modified Borg dyspnoea score at end exercise (mean difference (MD) -0.06 units, 95% CI -0.24-0.13; two studies, n=27). However, effects on exercise outcomes consistently favoured oxygen therapy. One study showed reduction in dyspnoea at rest with oxygen in patients who were acutely unwell (MD visual analogue scale 30 mm

Indexed as

Oxygen Inhalation TherapyAgedChi-Square DistributionDyspneaExercise ToleranceFemaleHumansLungLung Diseases, InterstitialMaleMiddle AgedQuality of LifeRecovery of FunctionTime FactorsTreatment Outcome

Identifiers

PMID28223395
PMCPMC9489021
OpenAlexW2590977977

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.