Evidence map›Paper›PMID 28223388›Full record

ArticleAntimicrobial agents and chemotherapy2017

Thomas Colley, Alexandre Alanio, Steven L Kelly, Gurpreet Sehra, Yasuo Kizawa, Andrew G S Warrilow, Josie E Parker, Diane E Kelly, Genki Kimura, Lauren Anderson-Dring and 14 more

Open access · hybridAbstract read
In one paragraph

Article in Antimicrobial agents and chemotherapy, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 41 papers.

0numbers the graph read from it
0cells of the map it votes in
41citing papers in PubMed
3.7field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

41 citing papers in PubMed, 83 citations in OpenAlex.

  1. Trial
  2. Pharmacological advances inJournal of enzyme inhibition and medicinal chemistry · 2026
    Review
  3. Review
  4. Article
  5. Article
  6. Review
  7. Emerging Applications of Triazole Antifungal Drugs.International journal of molecular sciences · 2026
    Review
  8. StudyingPharmaceuticals (Basel, Switzerland) · 2025
    Review
  9. Article
  10. Azole-ResistantJournal of fungi (Basel, Switzerland) · 2025
    Review
  11. Review
  12. Innovative antifungal strategies to combat drug-resistantFrontiers in cellular and infection microbiology · 2025
    Review
  13. Review
  14. Fungal lung disease.The European respiratory journal · 2024
    Review
  15. Review
  16. Accelerating the understanding ofCurrent research in microbial sciences · 2024
    Review
  17. Review
  18. Review
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

24 authors at 3 institutions in 3 countries.

Thomas ColleyPulmocide Ltd., London, United Kingdom.
Alexandre AlanioInstitut Pasteur, CNRS, Molecular Mycology Unit, French National Reference Center for Invasive Mycoses & Antifungals, URA3012, Paris, France.
Steven L KellyCentre for Cytochrome P450 Biodiversity, Institute of Life Science, Swansea University Medical School, Wales, United Kingdom.
Gurpreet SehraPulmocide Ltd., London, United Kingdom.
Yasuo KizawaNihon University, Chiba, Japan.
Andrew G S WarrilowCentre for Cytochrome P450 Biodiversity, Institute of Life Science, Swansea University Medical School, Wales, United Kingdom.
Josie E ParkerCentre for Cytochrome P450 Biodiversity, Institute of Life Science, Swansea University Medical School, Wales, United Kingdom.
Diane E KellyCentre for Cytochrome P450 Biodiversity, Institute of Life Science, Swansea University Medical School, Wales, United Kingdom.
Genki KimuraNihon University, Chiba, Japan.
Lauren Anderson-DringPulmocide Ltd., London, United Kingdom.
Takahiro NakaokiNihon University, Chiba, Japan.
Mihiro SunoseSygnature Discovery Ltd., Nottingham, United Kingdom.
Stuart OnionsSygnature Discovery Ltd., Nottingham, United Kingdom.
Damien CrepinSygnature Discovery Ltd., Nottingham, United Kingdom.
Franz LagasseSygnature Discovery Ltd., Nottingham, United Kingdom.
Matthew CrittallSygnature Discovery Ltd., Nottingham, United Kingdom.
Jonathan ShannonSygnature Discovery Ltd., Nottingham, United Kingdom.
Michael CookeSygnature Discovery Ltd., Nottingham, United Kingdom.
Stéphane BretagneInstitut Pasteur, CNRS, Molecular Mycology Unit, French National Reference Center for Invasive Mycoses & Antifungals, URA3012, Paris, France.
John King-UnderwoodCompchem Resource, Pendock, United Kingdom.
John MurrayPulmocide Ltd., London, United Kingdom.
Kazuhiro ItoPulmocide Ltd., London, United Kingdom kaz@pulmocide.com.
Pete StrongPulmocide Ltd., London, United Kingdom.
Garth RapeportPulmocide Ltd., London, United Kingdom.
Swansea University · GBNihon University · JPHôpital Saint-Louis · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The profile of PC945, a novel triazole antifungal designed for administration via inhalation, was assessed in a range of

Indexed as

AnimalsAntifungal AgentsAspergillosisAspergillus fumigatusBenzamidesCells, CulturedCytochrome P-450 Enzyme SystemFungal ProteinsHumansItraconazoleMiceMicrobial Sensitivity TestsTriazolesVoriconazoleAntifungal AgentsBenzamidescytochrome P-450 CYP51A, Aspergilluscytochrome P-450 CYP51B, AspergillusCytochrome P-450 Enzyme SystemFungal ProteinsItraconazolePC945 compoundposaconazoleTriazolesVoriconazoleAspergillus fumigatusazoleazole resistantCYP51inhalationlong acting

Identifiers

PMID28223388
PMCPMC5404542
OpenAlexW2589457164

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.