Evidence map›Paper›PMID 28223385›Full record

ArticleAntimicrobial agents and chemotherapy2017

Deletion of

Kun Li, Ting Li, Shan-Shan Yang, Xu-De Wang, Lei-Xin Gao, Rui-Qi Wang, Jing Gu, Xian-En Zhang, Jiao-Yu Deng

Open access · bronzeAbstract read
In one paragraph

Article in Antimicrobial agents and chemotherapy, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.3field-weighted citation impact, top 51% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 11 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Characterization ofFrontiers in microbiology · 2020
    Article
  7. Review
  8. Effects of cotrimoxazole prophylaxis onEmerging microbes & infections · 2019
    Observational
  9. Methionine AntagonizesFrontiers in cellular and infection microbiology · 2018
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Kun LiKey Laboratory of Agricultural and Environmental Microbiology, Wuhan Institute of Virology, Chinese Academy of Sciences, Wuhan, China.
Ting LiKey Laboratory of Agricultural and Environmental Microbiology, Wuhan Institute of Virology, Chinese Academy of Sciences, Wuhan, China.
Shan-Shan YangKey Laboratory of Agricultural and Environmental Microbiology, Wuhan Institute of Virology, Chinese Academy of Sciences, Wuhan, China.
Xu-De WangKey Laboratory of Agricultural and Environmental Microbiology, Wuhan Institute of Virology, Chinese Academy of Sciences, Wuhan, China.
Lei-Xin GaoKey Laboratory of Agricultural and Environmental Microbiology, Wuhan Institute of Virology, Chinese Academy of Sciences, Wuhan, China.
Rui-Qi WangKey Laboratory of Agricultural and Environmental Microbiology, Wuhan Institute of Virology, Chinese Academy of Sciences, Wuhan, China.
Jing GuKey Laboratory of Agricultural and Environmental Microbiology, Wuhan Institute of Virology, Chinese Academy of Sciences, Wuhan, China.
Xian-En ZhangNational Laboratory of Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing, China x.zhang@wh.iov.cn dengjy@wh.iov.cn.
Jiao-Yu DengKey Laboratory of Agricultural and Environmental Microbiology, Wuhan Institute of Virology, Chinese Academy of Sciences, Wuhan, China x.zhang@wh.iov.cn dengjy@wh.iov.cn.
Wuhan Institute of Virology · CNChinese Academy of Sciences · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Co-trimoxazole, a fixed-dose combination of sulfamethoxazole (SMX) and trimethoprim (TMP), has been used for the treatment of bacterial infections since the 1960s. Since it has long been assumed that the synergistic effects between SMX and TMP are the consequence of targeting 2 different enzymes of bacterial folate biosynthesis, 2 genes (

Indexed as

Anti-Bacterial AgentsEscherichia coliEscherichia coli ProteinsFolic Acid AntagonistsGene DeletionMicrobial Sensitivity TestsNeopterinPterinsPyrophosphatasesSalmonella entericaTetrahydrofolate DehydrogenaseTrimethoprim, Sulfamethoxazole Drug Combination7,8-dihydroneopterinAnti-Bacterial Agentsdihydroneopterin triphosphate pyrophosphohydrolasedihydropteroateEscherichia coli ProteinsFolic Acid AntagonistsFolM protein, E coliNeopterinNudB protein, E coliPterinsPyrophosphatasesTetrahydrofolate DehydrogenaseTrimethoprim, Sulfamethoxazole Drug CombinationnudBsulfamethoxazolesusceptibilitytetrahydromonapterintrimethoprim

Identifiers

PMID28223385
PMCPMC5404538
OpenAlexW2590084954

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.