Evidence map›Paper›PMID 28223379›Full record

ArticleAntimicrobial agents and chemotherapy2017

Mutations in

Ghady Haidar, Cornelius J Clancy, Ryan K Shields, Binghua Hao, Shaoji Cheng, M Hong Nguyen

Open access · bronzeAbstract read
In one paragraph

Article in Antimicrobial agents and chemotherapy, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 125 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
125citing papers in PubMed, 1 pooled it
7.4field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

125 citing papers in PubMed, 1 synthesis or guideline pooled it, 189 citations in OpenAlex.

  1. Pooled it
  2. Repeated emergence and fitness heterogeneity of KPC-33 in ST11Antimicrobial agents and chemotherapy · 2026
    Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. In vitro susceptibility ofNew microbes and new infections · 2025
    Review
  8. JAC-antimicrobial resistance · 2025
    Article
  9. Use of MALDI-TOF VITEK MS for rapid and efficient identification of KPC-type carbapenemases in Enterobacterales carrying the Tn4401a transposon.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2025
    Article
  10. Article
  11. Article
  12. Article
  13. Review
  14. Article
  15. Mechanisms leading toAntimicrobial agents and chemotherapy · 2024
    Article
  16. Emergence ofEuro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin · 2024
    Article
  17. Article
  18. Review
  19. Article
  20. Article

65 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Ghady HaidarUniversity of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, USA.ORCID 0000-0003-0634-8211
Cornelius J ClancyUniversity of Pittsburgh, Pittsburgh, Pennsylvania, USA cjc76@pitt.edu.
Ryan K ShieldsUniversity of Pittsburgh, Pittsburgh, Pennsylvania, USA.
Binghua HaoXDR Pathogen Laboratory, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, USA.
Shaoji ChengUniversity of Pittsburgh, Pittsburgh, Pennsylvania, USA.
M Hong NguyenUniversity of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, USA.
University of Pittsburgh · USUniversity of Pittsburgh Medical Center · US

Funding

Antibacterial Resistance Leadership Group (ARLG)UM1AI104681 · NIAID · DUKE UNIVERSITY · PI Vance G. Fowler, Henry F HENRY CHAMBERS · 2013 to 2026
$180.8M
Caspofungin pharmacokinetics-pharmacodynamics during intra-adbominal candidiasisK08AI114883 · NIAID · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI SHIELDS, RYAN K · 2015 to 2019
$858k
Evolution of KPC-K pneumoniae that persist in patients on prolonged antibioticsR21AI111037 · NIAID · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI CLANCY, CORNELIUS J · 2015 to 2016
$465k
NIAID NIH HHS K08 AI114883NIAID NIH HHS R21 AI111037NIAID NIH HHS UM1 AI104681
6 · The paper itself

Abstract

We identified four

Indexed as

Anti-Bacterial AgentsAzabicyclo CompoundsBacterial Proteinsbeta-Lactamase Inhibitorsbeta-LactamasesCarbapenem-Resistant EnterobacteriaceaeCarbapenemsCeftazidimeDrug CombinationsDrug Resistance, Multiple, BacterialEscherichia coliHumansKlebsiella pneumoniaeMicrobial Sensitivity TestsMutagenesis, Site-DirectedAnti-Bacterial Agentsavibactam, ceftazidime drug combinationAzabicyclo CompoundsBacterial Proteinsbeta-Lactamase Inhibitorsbeta-lactamase KPC-3, Klebsiella pneumoniaebeta-LactamasesCarbapenemsCeftazidimeDrug Combinationsceftazidime-avibactamdrug resistance mechanismsKPCsite-directed mutagenesis

Identifiers

PMID28223379
PMCPMC5404534
OpenAlexW2590149742

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.