Evidence map›Paper›PMID 28223359›Full record

ArticleThe Journal of biological chemistry2017

Peptide recognition by heterochromatin protein 1 (HP1) chromoshadow domains revisited: Plasticity in the pseudosymmetric histone binding site of human HP1.

Yanli Liu, Su Qin, Ming Lei, Wolfram Tempel, Yuzhe Zhang, Peter Loppnau, Yanjun Li, Jinrong Min

Open access · hybridAbstract read
In one paragraph

Article in The Journal of biological chemistry, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
1.1field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 44 citations in OpenAlex.

  1. Review
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  8. Characterization of the Swi6/HP1 binding motif in its partner protein reveals the basis for the functional divergence of the HP1 family proteins in fission yeast.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2025
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  15. Dominant-negative variants in CBX1 cause a neurodevelopmental disorder.Genetics in medicine : official journal of the American College of Medical Genetics · 2023
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  18. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Yanli LiuFrom the Structural Genomics Consortium, University of Toronto, Toronto, Ontario M5G 1L7, Canada and.
Su QinFrom the Structural Genomics Consortium, University of Toronto, Toronto, Ontario M5G 1L7, Canada and.
Ming LeiFrom the Structural Genomics Consortium, University of Toronto, Toronto, Ontario M5G 1L7, Canada and.
Wolfram TempelFrom the Structural Genomics Consortium, University of Toronto, Toronto, Ontario M5G 1L7, Canada and.
Yuzhe ZhangFrom the Structural Genomics Consortium, University of Toronto, Toronto, Ontario M5G 1L7, Canada and.
Peter LoppnauFrom the Structural Genomics Consortium, University of Toronto, Toronto, Ontario M5G 1L7, Canada and.
Yanjun LiFrom the Structural Genomics Consortium, University of Toronto, Toronto, Ontario M5G 1L7, Canada and.
Jinrong MinFrom the Structural Genomics Consortium, University of Toronto, Toronto, Ontario M5G 1L7, Canada and jr.min@utoronto.ca.
University of Toronto · CAStructural Genomics Consortium · CA

Funding

Wellcome Trust
6 · The paper itself

Abstract

Heterochromatin protein 1 (HP1), a highly conserved non-histone chromosomal protein in eukaryotes, plays important roles in the regulation of gene transcription. Each of the three human homologs of HP1 includes a chromoshadow domain (CSD). The CSD interacts with various proteins bearing the P

Indexed as

Amino Acid MotifsChromobox Protein Homolog 5Chromosomal Proteins, Non-HistoneCrystallography, X-RayHumansProtein DomainsCBX1 protein, humanChromobox Protein Homolog 5Chromosomal Proteins, Non-Histonechromatin regulationchromatin structureheterochromatinhistonepeptide interaction

Identifiers

PMID28223359
PMCPMC5392561
OpenAlexW2589191412

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.