Evidence map›Paper›PMID 28223348›Full record

ArticleInfection and immunity2017

Immunoactive Clostridial Membrane Vesicle Production Is Regulated by a Sporulation Factor.

Nozomu Obana, Ryoma Nakao, Kyoko Nagayama, Kouji Nakamura, Hidenobu Senpuku, Nobuhiko Nomura

Open access · bronzeAbstract read
In one paragraph

Article in Infection and immunity, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
1.4field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 38 citations in OpenAlex.

  1. Article
  2. Article
  3. Effect of different fermentation substrates on rumen microorganisms and microbe-derived extracellular vesicles (EVs).Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2025
    Article
  4. Article
  5. Review
  6. Review
  7. Article
  8. Article
  9. Article
  10. Article
  11. Membrane Vesicles Derived FromFrontiers in microbiology · 2022
    Article
  12. Article
  13. Review
  14. Article
  15. Article
  16. Review
  17. IgA-enhancing effects of membrane vesicles derived fromBioscience of microbiota, food and health · 2019
    Article
  18. The Therapeutic Benefit of Bacterial Membrane Vesicles.International journal of molecular sciences · 2017
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Nozomu ObanaFaculty of Life and Environmental Sciences, University of Tsukuba, Tsukuba, Japan.
Ryoma NakaoDepartment of Bacteriology I, National Institute of Infectious Diseases, Tokyo, Japan.
Kyoko NagayamaGraduate School of Life and Environmental Sciences, University of Tsukuba, Tsukuba, Japan.
Kouji NakamuraFaculty of Life and Environmental Sciences, University of Tsukuba, Tsukuba, Japan.
Hidenobu SenpukuDepartment of Bacteriology I, National Institute of Infectious Diseases, Tokyo, Japan.
Nobuhiko NomuraFaculty of Life and Environmental Sciences, University of Tsukuba, Tsukuba, Japan nomura.nobuhiko.ge@u.tsukuba.ac.jp.
University of Tsukuba · JPNational Institute of Infectious Diseases · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Recently, many Gram-positive bacteria as well as Gram-negative bacteria have been reported to produce membrane vesicles (MVs), but little is known regarding the regulators involved in MV formation. We found that a Gram-positive anaerobic pathogen,

Indexed as

Gene Expression Regulation, BacterialAnimalsAntigens, BacterialCell LineClostridium perfringensHost-Pathogen InteractionsInterleukin-6MacrophagesMiceSecretory VesiclesSignal TransductionToll-Like Receptor 3Transcription FactorsAntigens, BacterialInterleukin-6interleukin-6, mouseTLR3 protein, mouseToll-Like Receptor 3Transcription FactorsClostridium perfringensinnate immunitymembrane vesiclesporulation

Identifiers

PMID28223348
PMCPMC5400848
OpenAlexW2590146292

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.