ArticleThe Journal of cell biology2017
A
Open access · bronzeAbstract read
In one paragraph
Article in The Journal of cell biology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
4.6field-weighted citation impact, top 5% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
22 citing papers in PubMed, 45 citations in OpenAlex.
- RNA-binding proteins and ribonucleoproteins as determinants of immunity.Nature reviews. Immunology · 2026Review
- The role of RNA binding proteins in cancer biology: A focus on FMRP.Genes & diseases · 2025Review
- Understanding pathophysiology in fragile X syndrome: a comprehensive review.Neurogenetics · 2024Review
- From wings to whiskers to stem cells: why every model matters in fragile X syndrome research.Journal of neurodevelopmental disorders · 2024Review
- Comprehensive analysis of mJournal of translational medicine · 2023Article
- Looking at the Pretty "Phase" of Membraneless Organelles: A View FromFrontiers in cell and developmental biology · 2022Review
- Altered expression of fragile X mental retardation-1 (FMR1) in the thymus in autoimmune myasthenia gravis.Journal of neuroinflammation · 2021Article
- Neuronal fragile X mental retardation protein activates glial insulin receptor mediated PDF-Tri neuron developmental clearance.Nature communications · 2021Article
- The RNA-binding fragile-X mental retardation protein and its role beyond the brain.Biophysical reviews · 2020Review
- Genetic background mutations drive neural circuit hyperconnectivity in a fragile X syndrome model.BMC biology · 2020Article
- Reduced serum levels of pro-inflammatory chemokines in fragile X syndrome.BMC neurology · 2020Article
- Repurposing Fragile X Drugs to Inhibit SARS-CoV-2 Viral Reproduction.Frontiers in cell and developmental biology · 2020Article
- Review
- Review
- The ABC TransporterG3 (Bethesda, Md.) · 2018Article
- Article
- Modeling Fragile X Syndrome inFrontiers in molecular neuroscience · 2018Review
- Modeling Inflammation in Autism Spectrum Disorders Using Stem Cells.Frontiers in pediatrics · 2018Review
- Multifarious Functions of the Fragile X Mental Retardation Protein.Trends in genetics : TIG · 2017Review
- ESCRT-III Membrane Trafficking Misregulation Contributes To Fragile X Syndrome Synaptic Defects.Scientific reports · 2017Article
Corrections and comments
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Authors and funding
15 authors at 2 institutions in 1 country.
Reed M O'ConnorDepartment of Genetics and Development, Columbia University Medical Center, New York, NY 10032.
Elizabeth F StoneDepartment of Genetics and Development, Columbia University Medical Center, New York, NY 10032.ORCID 0000-0002-4148-7957
Charlotte R WayneDepartment of Genetics and Development, Columbia University Medical Center, New York, NY 10032.ORCID 0000-0003-4622-4627
Emily V MarcinkeviciusDepartment of Genetics and Development, Columbia University Medical Center, New York, NY 10032.
Matt UlgheraitDepartment of Genetics and Development, Columbia University Medical Center, New York, NY 10032.
Rebecca DelventhalDepartment of Genetics and Development, Columbia University Medical Center, New York, NY 10032.ORCID 0000-0002-0920-0004
Meghan M PantaliaDepartment of Genetics and Development, Columbia University Medical Center, New York, NY 10032.
Vanessa M HillDepartment of Genetics and Development, Columbia University Medical Center, New York, NY 10032.ORCID 0000-0002-8852-3708
Clarice G ZhouDepartment of Biological Sciences, Columbia University, New York, NY 10025.ORCID 0000-0001-7390-1692
Sophie McAllisterDepartment of Biological Sciences, Columbia University, New York, NY 10025.
Anna ChenDepartment of Biological Sciences, Columbia University, New York, NY 10025.ORCID 0000-0002-5946-6572
Jennifer S ZiegenfussDepartment of Physiology and Cellular Biophysics, Columbia University Medical Center, New York, NY 10032.
Wesley B GrueberDepartment of Physiology and Cellular Biophysics, Columbia University Medical Center, New York, NY 10032.
Julie C CanmanDepartment of Pathology and Cell Biology, Columbia University Medical Center, New York, NY 10032.ORCID 0000-0001-8135-2072
Mimi M Shirasu-HizaDepartment of Genetics and Development, Columbia University Medical Center, New York, NY 10032 ms4095@cumc.columbia.edu.ORCID 0000-0002-2730-1765
Columbia University Irving Medical Center · USColumbia University · US
Funding
MEDICAL SCIENTIST TRAINING PROGRAMT32GM007367 · NIGMS · COLUMBIA UNIV NEW YORK MORNINGSIDE · PI REINER, STEVEN L · 1985 to 2021
$25.1MTRAINING IN CELLULAR, MOLECULAR AND BIOPHYSICAL STUDIEST32GM008224 · NIGMS · COLUMBIA UNIV NEW YORK MORNINGSIDE · PI LIEM, RONALD K. · 1987 to 2021
$9.9MHormones: Molecular Mechanism of Action and FunctionsT32DK007328 · NIDDK · COLUMBIA UNIV NEW YORK MORNINGSIDE · PI KOUSTENI, STAVROULA · 1986 to 2025
$7.8MPREDOCTORAL TRAINING GRANT IN HUMAN GENETICS &DEVELOPMET32GM007088 · NIGMS · COLUMBIA UNIV NEW YORK MORNINGSIDE · PI SHEN, MICHAEL M. · 1985 to 2020
$7.1MCircadian-Regulated Aging PhysiologiesR01AG045842 · NIA · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI Michele M Shirasu-Hiza · 2013 to 2026
$5.1MCircadian regulation of physiological functionsR35GM127049 · NIGMS · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI Michele M Shirasu-Hiza · 2018 to 2026
$3.9MCell type-variation of cytokinesisR01GM117407 · NIGMS · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI CANMAN, JULIE C · 2016 to 2023
$2.9MIR-LAMP: Optigenetic technology to spatially manipulate protein function in vivoDP2OD008773 · OD · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI CANMAN, JULIE C · 2011 to 2011
$2.4MCircadian regulation of phagocytosisR01GM105775 · NIGMS · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI SHIRASU-HIZA, MICHELE M · 2013 to 2017
$1.6MPhagocytosis is misregulated in a Drosophila model of Fragile X syndromeF31NS080673 · NINDS · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI STONE, ELIZABETH FREDA · 2013 to 2014
$70kNIA NIH HHS R01 AG045842NIDDK NIH HHS T32 DK007328NIGMS NIH HHS R01 GM105775NIGMS NIH HHS R01 GM117407NIGMS NIH HHS R35 GM127049NIGMS NIH HHS T32 GM007088NIGMS NIH HHS T32 GM007367NIGMS NIH HHS T32 GM008224NIH HHS DP2 OD008773
Abstract
Fragile X syndrome, the most common known monogenic cause of autism, results from the loss of FMR1, a conserved, ubiquitously expressed RNA-binding protein. Recent evidence suggests that Fragile X syndrome and other types of autism are associated with immune system defects. We found that
Indexed as
AnimalsBrainDisease Models, AnimalDrosophila melanogasterDrosophila ProteinsFragile X Messenger Ribonucleoprotein 1Fragile X SyndromeImmunity, InnateLearningMaleMemoryMushroom BodiesNeurogliaNeuronsPhagocytosisRNA-Binding ProteinsDrosophila ProteinsFragile X Messenger Ribonucleoprotein 1RNA-Binding Proteins
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What OpenQuestion holds
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Read underepoch 390
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.