Evidence map›Paper›PMID 28223312›Full record

ArticleGenes & development2017

Natural variation and dosage of the HEI10 meiotic E3 ligase control

Piotr A Ziolkowski, Charles J Underwood, Christophe Lambing, Marina Martinez-Garcia, Emma J Lawrence, Liliana Ziolkowska, Catherine Griffin, Kyuha Choi, F Chris H Franklin, Robert A Martienssen and 1 more

Open access · diamondAbstract read
In one paragraph

Article in Genes & development, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 122 papers.

0numbers the graph read from it
0cells of the map it votes in
122citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

122 citing papers in PubMed, 203 citations in OpenAlex.

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  13. Structure and function of the synaptonemal complex.The Journal of cell biology · 2026
    Review
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62 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 3 countries.

Piotr A ZiolkowskiDepartment of Plant Sciences, University of Cambridge, Cambridge CB2 3EA, United Kingdom.
Charles J UnderwoodDepartment of Plant Sciences, University of Cambridge, Cambridge CB2 3EA, United Kingdom.
Christophe LambingDepartment of Plant Sciences, University of Cambridge, Cambridge CB2 3EA, United Kingdom.
Marina Martinez-GarciaSchool of Biosciences, University of Birmingham, Birmingham B15 2TT, United Kingdom.
Emma J LawrenceDepartment of Plant Sciences, University of Cambridge, Cambridge CB2 3EA, United Kingdom.
Liliana ZiolkowskaDepartment of Plant Sciences, University of Cambridge, Cambridge CB2 3EA, United Kingdom.
Catherine GriffinDepartment of Plant Sciences, University of Cambridge, Cambridge CB2 3EA, United Kingdom.
Kyuha ChoiDepartment of Plant Sciences, University of Cambridge, Cambridge CB2 3EA, United Kingdom.
F Chris H FranklinSchool of Biosciences, University of Birmingham, Birmingham B15 2TT, United Kingdom.
Robert A MartienssenHoward Hughes Medical Institute, Gordon and Betty Moore Foundation, Watson School of Biological Sciences, Cold Spring Harbor Laboratory, Cold Spring Harbor, New York 11724, USA.
Ian R HendersonDepartment of Plant Sciences, University of Cambridge, Cambridge CB2 3EA, United Kingdom.
University of Cambridge · GBUniversity of Birmingham · GBCold Spring Harbor Laboratory · USGordon and Betty Moore Foundation · US

Funding

Transposons, RNA Interference and HeterochromatinR01GM067014 · NIGMS · COLD SPRING HARBOR LABORATORY · PI MARTIENSSEN, ROBERT A · 2003 to 2016
$4.1M
Biotechnology and Biological Sciences Research Council BB/K007882/1Biotechnology and Biological Sciences Research Council BB/M004937/1Biotechnology and Biological Sciences Research Council BB/N007557/1NIGMS NIH HHS R01 GM067014
6 · The paper itself

Abstract

During meiosis, homologous chromosomes undergo crossover recombination, which creates genetic diversity and balances homolog segregation. Despite these critical functions, crossover frequency varies extensively within and between species. Although natural crossover recombination modifier loci have been detected in plants, causal genes have remained elusive. Using natural

Indexed as

Crossing Over, GeneticGene DosageAmino Acid SequenceArabidopsisArabidopsis ProteinsChromosomal Proteins, Non-HistoneMeiosisQuantitative Trait LociRecombination, GeneticSequence Homology, Amino AcidArabidopsis ProteinsChromosomal Proteins, Non-HistoneHEI10 protein, ArabidopsisArabidopsisHEI10meiosismodifierrecombinationZMM

Identifiers

PMID28223312
PMCPMC5358726
OpenAlexW2590788677

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.