Evidence map›Paper›PMID 28223082›Full record

Trial reportThe American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry2017

Negative Emotions and Suicidal Ideation during Psychosocial Treatments in Older Adults with Major Depression and Cognitive Impairment.

Dimitris N Kiosses, James J Gross, Samprit Banerjee, Paul R Duberstein, David Putrino, George S Alexopoulos

Registry-linked trialAbstract readRandomized Controlled Trial
In one paragraph

Trial report in The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT00368940 (A Treatment for Depressed, Cognitively Impaired Elders), which is not on this map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
5.5field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT00368940 nacompletednot on this map

A Treatment for Depressed, Cognitively Impaired Elders

TypeinterventionalSponsorWeill Medical College of Cornell UniversityRan2006 to 2011Enrolled74ConditionsDepressionArmsPATH, ST-CI
3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 43 citations in OpenAlex.

  1. Article
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  3. Suicidal Ideation After Hip Fracture in Older Adults.Psychogeriatrics : the official journal of the Japanese Psychogeriatric Society · 2025
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Dimitris N KiossesDepartment of Psychiatry, Weill-Cornell Institute of Geriatric Psychiatry, Weill Cornell Medical College, White Plains, NY. Electronic address: dkiosses@med.cornell.edu.
James J GrossDepartment of Psychology, Stanford University, Stanford, CA.
Samprit BanerjeeDepartment of Healthcare Policy and Research, Weill-Cornell Institute of Geriatric Psychiatry, Weill Cornell Medical College, White Plains, NY.
Paul R DubersteinDepartment of Psychiatry and Family Medicine, University of Rochester Medical Center, Rochester, NY.
David PutrinoDepartment of Rehabilitation Medicine, Weill Cornell Medicine, White Plains, NY; Telemedicine and Virtual Rehabilitation, Burke Medical Research Institute, White Plains, NY.
George S AlexopoulosDepartment of Psychiatry, Weill-Cornell Institute of Geriatric Psychiatry, Weill Cornell Medical College, White Plains, NY.
Cornell University · USStanford University · USUniversity of Rochester Medical Center · US

Funding

Research Methods CoreP30MH085943 · NIMH · WEILL MEDICAL COLL OF CORNELL UNIV · PI ALEXOPOULOS, GEORGE S · 2009 to 2013
$9.2M
Home-Delivered Intervention for Depressed, Cognitively Impaired EldersR01MH091045 · NIMH · WEILL MEDICAL COLL OF CORNELL UNIV · PI KIOSSES, DIMITRIS N · 2011 to 2015
$1.8M
Treating Depressed, Cognitively Impaired EldersK23MH074659 · NIMH · WEILL MEDICAL COLL OF CORNELL UNIV · PI KIOSSES, DIMITRIS N · 2006 to 2010
$802k
NIMH NIH HHS K23 MH074659NIMH NIH HHS P30 MH085943NIMH NIH HHS R01 MH091045
6 · The paper itself

Abstract

objectiveTo examine the relationship of negative emotions with suicidal ideation during 12 weeks of Problem Adaptation Therapy (PATH) versus Supportive Therapy of Cognitively Impaired Older Adults (ST-CI), hypothesizing that improved negative emotions are associated with reduced suicidal ideation, PATH improves negative emotions more than ST-CI, and improved negative emotions, rather than other depression symptoms, predict reduction in suicidal ideation.

methodsIn a randomized controlled trial of two home-delivered psychosocial interventions, 74 older participants (65-95 years old) with major depressive disorder and cognitive impairment were recruited in collaboration with community agencies. The sample reported less intense feelings than suicidal intention. Interventions and assessments were conducted in participants' homes. PATH focuses on improving emotion regulation, whereas ST-CI focuses on nonspecific therapeutic factors, such as understanding and empathy. Improved negative emotions were measured as improvement in Montgomery Asberg's Depression Rating Scales' (MADRS) observer ratings of sadness, anxiety, guilt, hopelessness, and anhedonia. Suicidal ideation was assessed with the MADRS Suicide Item.

resultsMADRS Negative Emotions scores were significantly associated with suicidal ideation during the course of treatment (F

conclusionFindings thatimprovement in negative emotions mediates reduction in suicidal ideation may guide the development of psychosocial interventions for reduction of suicidal ideation (clinicaltrials.gov; NCT00368940).

Indexed as

EmotionsSuicidal IdeationAgedAged, 80 and overCognitive DysfunctionHome Care ServicesHumansMajor Depressive DisorderMalePsychotherapycognitive impairmentdepressionemotional statesEmotionspsychosocial treatmentsuicidal ideationsuicide

Identifiers

PMID28223082
PMCPMC5429870
OpenAlexW2578325165

What OpenQuestion holds

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Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.