Evidence map›Paper›PMID 28222782›Full record

ArticleJournal of translational medicine2017

Identification of miRNA-mRNA crosstalk in CD4

Qibin Liao, Jin Wang, Zenglin Pei, Jianqing Xu, Xiaoyan Zhang

Erratum issuedOpen access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of translational medicine, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.0field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Correction to: Identification of miRNA-mRNA crosstalk in CD4Journal of translational medicine · 2020
    Article
  5. Article
  6. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Qibin LiaoShanghai Public Health Clinical Center, Fudan University, Shanghai, China.
Jin WangShanghai Public Health Clinical Center, Fudan University, Shanghai, China.
Zenglin PeiShanghai Public Health Clinical Center, Fudan University, Shanghai, China.
Jianqing XuShanghai Public Health Clinical Center, Fudan University, Shanghai, China. xujianqing@shphc.org.cn.
Xiaoyan ZhangShanghai Public Health Clinical Center, Fudan University, Shanghai, China. zhangxiaoyan@shaphc.org.
Shanghai Public Health Clinical Center · CNFudan University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundHIV-1-infected long-term nonprogressors (LTNPs) are characterized by infection with HIV-1 more than 7-10 years, but keeping high CD4

methodsTo identify microRNAs (miRNAs) and their target genes related to distinct clinical outcomes in HIV-1 infection, we performed the integrative transcriptome analyses in two series GSE24022 and GSE6740 by GEO2R, R, TargetScan, miRDB, and Cytoscape softwares. The functional pathways of these differentially expressed miRNAs (DEMs) targeting genes were further analyzed with DAVID.

resultsWe identified that 7 and 19 DEMs in CD4

conclusionsIntegrative transcriptome analyses showed that distinct transcriptional profiles in CD4

Indexed as

Gene Expression ProfilingCD4-Positive T-LymphocytesDisease ProgressionGene Regulatory NetworksHIV-1HIV InfectionsHumansMicroRNAsMolecular Sequence AnnotationRNA, MessengerMicroRNAsRNA, MessengerClinical outcomeHIV-1Integrative transcriptome analyses

Identifiers

PMID28222782
PMCPMC5319073
OpenAlexW2589552173

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.