Evidence map›Paper›PMID 28222701›Full record

Observational studyBMC anesthesiology2017

The effect of deep muscle relaxation on the force required during Latissimus Dorsi dissection for breast reconstructive surgery: results of a prospective, double-blinded observational pilot study.

T Ledowski, A Goodwin-Walters, P Quinn, M Calvert

Open access · goldAbstract readObservational Study
In one paragraph

Observational study in BMC anesthesiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact, top 98% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

T LedowskiAnaesthesiology Unit in School of Medicine and Pharmacology, University of Western Australia, Level 2, Royal Perth Hospital Medical Research Foundation Building, Rear 50 Murray Street, Perth, WA, 6000, Australia. Thomas.ledowski@health.wa.gov.au.
A Goodwin-WaltersDepartment of Plastic and Reconstructive Surgery, Royal Perth Hospital, 197 Wellington Street, Perth, WA, 6000, Australia.
P QuinnDepartment of Plastic and Reconstructive Surgery, Royal Perth Hospital, 197 Wellington Street, Perth, WA, 6000, Australia.
M CalvertDepartment of Anaesthesia and Pain Medicine, Royal Perth Hospital, 197 Wellington Street, Perth, WA, 6000, Australia.
Royal Perth Hospital · AUUniversity of Western Australia · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe use of neuromuscular blocking agents has previously been suggested to facilitate the dissection of the latissimus dorsi muscle during breast reconstructive surgery. The aim of this study was to quantify the influence of deep muscle relaxation on the force required to lift the latissimus dorsi muscle during flap preparation.

methodsAfter ethics approval and written informed consent 15 patients scheduled for elective breast reconstruction with a latissimus dorsi pedicled flap (muscle flap, not myocutaneous flap) under general anaesthesia were prospectively included. Midway through the muscle dissection a sterile cotton tape was slung around the mid portion of the muscle and connected with a sterile strain gauge stably positioned just above the patient. Thereafter, the muscle was lifted by moving the strain gauge vertically upwards until a muscle tension similar to that created manually during muscle dissection was achieved. The force (N) and distance required to tension the muscle were recorded and the tension released. In a randomized and blinded crossover design either rocuronium (0.6 mg.kg

resultsMuscle relaxation significantly reduced the force for flap tensioning (median [percentiles] - 22 [-32/-13] %; P = 0.011) in 10/15 patients. However, in the remaining 5 patients no significant effect was measured. Normal saline had no effect on the measured force.

conclusionsDeep muscle relaxation significantly reduces the force required to manually elevate the latissimus dorsi muscle during its dissection in the majority of but not all patients.

trial registrationThe study was retrospectively registered on [17.6.2014] with the Australian and New Zealand Clinical Trials Registry. ACTRN12614000637640.

Indexed as

MammaplastyMuscle RelaxationSurgical FlapsAndrostanolsAnesthesia, GeneralDouble-Blind MethodFemaleHumansMiddle AgedNeuromuscular Nondepolarizing AgentsPilot ProjectsProspective StudiesRocuroniumSuperficial Back MusclesAndrostanolsNeuromuscular Nondepolarizing AgentsRocuroniumBreast reconstructive surgeryLatissimus dorsi flapMuscle tensionNeuromuscular blocking agentsRocuronium

Identifiers

PMID28222701
PMCPMC5319183
OpenAlexW2589800440

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.