Evidence map›Paper›PMID 28222630›Full record

SynthesisThe Journal of international medical research2017

Association of VDR polymorphisms ( Taq I and Bsm I) with prostate cancer: a new meta-analysis.

Sheng Liu, Hairong Cai, Weisong Cheng, Haitao Zhang, Zhengbo Pan, Dongguo Wang

Abstract readMeta-Analysis
In one paragraph

Synthesis in The Journal of international medical research, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Review
  4. Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. Vitamin D receptorOncotarget · 2018
    Article
  10. Article
  11. Review
  12. Review
  13. DHPLC Elution Patterns ofCancer genomics & proteomics
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Sheng Liu1 Department of Urology Surgery, Taizhou University Affiliated Taizhou Municipal Hospital, Taizhou, China.
Hairong Cai1 Department of Urology Surgery, Taizhou University Affiliated Taizhou Municipal Hospital, Taizhou, China.
Weisong Cheng1 Department of Urology Surgery, Taizhou University Affiliated Taizhou Municipal Hospital, Taizhou, China.
Haitao Zhang1 Department of Urology Surgery, Taizhou University Affiliated Taizhou Municipal Hospital, Taizhou, China.
Zhengbo Pan1 Department of Urology Surgery, Taizhou University Affiliated Taizhou Municipal Hospital, Taizhou, China.
Dongguo Wang2 Department of Clinical Laboratory Medicine, Taizhou University Affiliated Taizhou Municipal Hospital, Taizhou, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective Prostate cancer is a malignant tumour that poses a serious risk to human health. Epidemiological studies suggest that it may be associated with vitamin D receptor gene ( VDR) polymorphisms. Previous work investigated potential risks between Taq I (rs731236) and Bsm I (rs1544410) VDR polymorphisms with prostate cancer in humans; however, results are inconsistent. Methods We conducted a meta-analysis to retrieve genetic association analyses of rs731236 and rs1544410 polymorphisms with prostate cancer from studies published between 2006-2016. Pooled odds ratios with 95% confidence intervals were used to assess genetic associations, and heterogeneity was assessed by Q and I

Indexed as

Genetic Predisposition to DiseasePolymorphism, Single NucleotideAsian PeopleBlack or African AmericanBlack PeopleDeoxyribonucleases, Type II Site-SpecificGene ExpressionHumansMaleModels, GeneticOdds RatioProstatic NeoplasmsReceptors, CalcitriolRiskTaq PolymeraseWhite PeopleDeoxyribonucleases, Type II Site-Specificendodeoxyribonuclease BsmIReceptors, CalcitriolTaq PolymeraseVDR protein, humanBsm Imeta-analysispolymorphismsprostate cancerTaq IVDR

Identifiers

PMID28222630
PMCPMC5536582

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.