Evidence map›Paper›PMID 28222629›Full record

ArticleThe Journal of international medical research2017

Relationship between hyperuricemia and risk of coronary heart disease in a middle-aged and elderly Chinese population.

Ye Yang, Jian Tian, Chao Zeng, Jie Wei, Liang-Jun Li, Xi Xie, Tuo Yang, Hui Li, Guang-Hua Lei

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in The Journal of international medical research, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.2field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 21 citations in OpenAlex.

  1. Review
  2. Article
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  9. Nomogram Based on Risk Factors for Type 2 Diabetes Mellitus Patients with Coronary Heart Disease.Diabetes, metabolic syndrome and obesity : targets and therapy · 2020
    Article
  10. Observational
  11. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Ye Yang1 Department of Orthopaedics, Xiangya Hospital, Central South University, Changsha, Hunan Province, China.
Jian Tian1 Department of Orthopaedics, Xiangya Hospital, Central South University, Changsha, Hunan Province, China.
Chao Zeng1 Department of Orthopaedics, Xiangya Hospital, Central South University, Changsha, Hunan Province, China.
Jie Wei2 Health Management Centre, Xiangya Hospital, Central South University, Changsha, Hunan Province, China.
Liang-Jun Li1 Department of Orthopaedics, Xiangya Hospital, Central South University, Changsha, Hunan Province, China.
Xi Xie1 Department of Orthopaedics, Xiangya Hospital, Central South University, Changsha, Hunan Province, China.
Tuo Yang1 Department of Orthopaedics, Xiangya Hospital, Central South University, Changsha, Hunan Province, China.
Hui Li1 Department of Orthopaedics, Xiangya Hospital, Central South University, Changsha, Hunan Province, China.
Guang-Hua Lei1 Department of Orthopaedics, Xiangya Hospital, Central South University, Changsha, Hunan Province, China.
Central South University · CNXiangya Hospital Central South University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective To investigate the relationship between hyperuricemia and coronary heart disease (CHD) risk based on the Framingham risk score (FRS) in a middle-aged and elderly Chinese population. Methods This cross-sectional study enrolled patients undergoing routine check-ups at Xiangya Hospital between October 2013 and November 2014. Hyperuricemia was defined as uric acid ≥416 mmol/l for males and ≥360 mmol/l for females. A 10-year CHD risk was calculated from FRS. A multivariable logistic analysis model was used to evaluate associations. Results Of the 6347 patients, 3415 (53.8%) were male, 1543 (24.3%) had a CHD risk ≥10% (i.e. intermediate and high risk) and the prevalence of hyperuricemia was 18.1% ( n = 1148). After adjusting for potential confounding factors, the 10-year CHD risk was increased in patients with hyperuricemia compared with those without hyperuricemia by 0.28 times in the total population (odds ratio [OR] 1.28; 95% confidence interval [CI] 1.09, 1.48), by 0.25 times in the male population (OR 1.25; 95% CI 1.06, 1.47) and by 2.76 times in the female population (OR 3.76; 95% CI 2.08, 6.79). Conclusion Hyperuricemia was positively associated with a 10-year risk of CHD suggesting that it might be an independent CHD risk factor in middle-aged and elderly individuals.

Indexed as

AgedAsian PeopleBiomarkersChinaCoronary DiseaseCross-Sectional StudiesFemaleHumansHyperuricemiaLogistic ModelsMaleMiddle AgedOdds RatioPrevalenceRiskSex FactorsBiomarkersUric Acidcoronary heart disease riskFramingham risk scoreHyperuricemia

Identifiers

PMID28222629
PMCPMC5536609
OpenAlexW2574061583

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.