Evidence map›Paper›PMID 28222625›Full record

SynthesisThe Journal of international medical research2017

Shortened preoperative fasting for prevention of complications associated with laparoscopic cholecystectomy: a meta-analysis.

Duo Xu, Xuejiao Zhu, Yuan Xu, Liqing Zhang

Registry-linked trialOpen access · goldAbstract readMeta-Analysis
In one paragraph

Synthesis in The Journal of international medical research, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06349382 (Preoperative Oral Carbohydrate Loading in Aortic Surgery), which is not on this map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
2.7field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06349382 nacompletednot on this mapstarted 2024, after this paper: background citation

Preoperative Oral Carbohydrate Loading in Aortic Surgery

TypeinterventionalSponsorUniversity of BelgradeRan2024 to 2025Enrolled40ConditionsAbdominal Aortic Aneurysm, Leriche SyndromeArmscarbohydrate-rich beverage
3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 47 citations in OpenAlex.

  1. Trial
  2. Trial
  3. Trial
  4. The effect of oral protein and carbohydrate solution administration on NLR, IL-6 and CRP levels in patients undergoing surgery.Journal of critical care medicine (Universitatea de Medicina si Farmacie din Targu-Mures) · 2026
    Article
  5. Article
  6. Drink lemonade! Implementation of drinking 2 h before elective orthopedic surgery to reduce prolonged fasting.Nutrition in clinical practice : official publication of the American Society for Parenteral and Enteral Nutrition · 2025
    Article
  7. Article
  8. Observational
  9. Review
  10. Article
  11. Article
  12. Article
  13. Fasting and surgery timing (FaST) audit.Clinical nutrition (Edinburgh, Scotland) · 2021
    Article
  14. Article
  15. Article
  16. Review
  17. Review
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Duo Xu1 The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, China.
Xuejiao Zhu2 Hangzhou Normal University, Hangzhou, China.
Yuan Xu3 The Second Affiliated Hospital of Wenzhou Medical University, Wenzhou, China.
Liqing Zhang1 The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, China.
Wenzhou Medical University · CNHangzhou Normal University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective Routine fasting (12 h) is always applied before laparoscopic cholecystectomy, but prolonged preoperative fasting causes thirst, hunger, and irritability as well as dehydration, low blood glucose, insulin resistance and other adverse reactions. We assessed the safety and efficacy of a shortened preoperative fasting period in patients undergoing laparoscopic cholecystectomy. Methods We searched PubMed, Embase and Cochrane Central Register of Controlled Trials up to 20 November 2015 and selected controlled trials with a shortened fasting time before laparoscopic cholecystectomy. We assessed the results by performing a meta-analysis using a variety of outcome measures and investigated the heterogeneity by subgroup analysis. Results Eleven trials were included. Forest plots showed that a shortened fasting time reduced the operative risk and patient discomfort. A shortened fasting time also reduced postoperative nausea and vomiting as well as operative vomiting. With respect to glucose metabolism, a shortened fasting time significantly reduced abnormalities in the ratio of insulin sensitivity. The C-reactive protein concentration was also reduced by a shortened fasting time. Conclusions A shortened preoperative fasting time increases patients' postoperative comfort, improves insulin resistance, and reduces stress responses. This evidence supports the clinical application of a shortened fasting time before laparoscopic cholecystectomy.

Indexed as

Analysis of VarianceCholecystectomy, LaparoscopicC-Reactive ProteinDehydrationFastingHumansHypoglycemiaInsulin ResistancePostoperative Nausea and VomitingPreoperative CarePreoperative PeriodStress, PhysiologicalTime FactorsC-Reactive Proteincomplicationslaparoscopic cholecystectomymeta-analysisShortened preoperative fasting

Identifiers

PMID28222625
PMCPMC5536598
OpenAlexW2579372945

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.