ArticleThe Journal of international medical research2017
Abnormality of spontaneous brain activities in patients with chronic neck and shoulder pain: A resting-state fMRI study.
Article in The Journal of international medical research, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04735159 (Development of a Predictive Model of Effectiveness for the Implantation of Electrical Neurostimulators in Patients With Chronic Pain Using Imaging Biomarkers Extracted From Magnetic Resonance), which is not on this map. Cited by 19 papers, 2 of them syntheses that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Development of a Predictive Model of Effectiveness for the Implantation of Electrical Neurostimulators in Patients With Chronic Pain Using Imaging Biomarkers Extracted From Magnetic Resonance
Who cites it
19 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Abnormalities of brain structure and function in cervical spondylosis: a multi-modal voxel-based meta-analysis.Frontiers in neuroscience · 2024Pooled it
- Meta-analysis of resting-state fMRI in cervical spondylosis patients using AES-SDM.Frontiers in neurology · 2024Pooled it
- Trial
- Abnormal lymphatic system function in patients with chronic neck and shoulder pain: neuroimaging evidence from DTI-ALPS.Frontiers in molecular neuroscience · 2026Article
- Predicting acupuncture efficacy for neck pain based on functional connectivity features: a machine learning study.Annals of medicine · 2025Article
- Assessing the Modulatory Effects of tDCS and Acupuncture on Cerebral Blood Flow in Chronic Low Back Pain Using Arterial Spin Labeling Perfusion Imaging.Brain sciences · 2025Article
- Multi-network dynamical structure of the human brain in the setting of chronic pain: a coordinate-based meta-analysis.Brain communications · 2025Article
- Investigating the brain functional abnormalities underlying pain hypervigilance in chronic neck and shoulder pain: a resting-state fMRI study.Neuroradiology · 2024Article
- Resting-state brain activity as a biomarker of chronic pain impairment and a mediator of its association with pain resilience.Human brain mapping · 2024Article
- Cannabinoids for Acute Pain Management: Approaches and Rationale.Current pain and headache reports · 2024Review
- Functional Brain Changes in Younger Population of Cervical Spondylosis Patients with Chronic Neck Pain.Journal of pain research · 2024Article
- Modulation effect of acupuncture treatment on chronic neck and shoulder pain in female patients: Evidence from periaqueductal gray-based functional connectivity.CNS neuroscience & therapeutics · 2022Article
- Image Features of Resting-State Functional Magnetic Resonance Imaging in Evaluating Poor Emotion and Sleep Quality in Patients with Chronic Pain under Artificial Intelligence Algorithm.Contrast media & molecular imaging · 2022Article
- A Longitudinal Study on Attenuated Structural Covariance in Patients With Somatic Symptom Disorder.Frontiers in psychiatry · 2022Article
- Abnormal Dynamics of Functional Connectivity Density Associated With Chronic Neck Pain.Frontiers in molecular neuroscience · 2022Article
- Volumetric and functional connectivity alterations in patients with chronic cervical spondylotic pain.Neuroradiology · 2020Article
- Static and Dynamic Changes of Amplitude of Low-Frequency Fluctuations in Cervical Discogenic Pain.Frontiers in neuroscience · 2020Article
- Altered intrinsic brain activity and regional cerebral blood flow in patients with chronic neck and shoulder pain.Polish journal of radiology · 2020Article
- Different mechanisms of contralateral- or ipsilateral-acupuncture to modulate the brain activity in patients with unilateral chronic shoulder pain: a pilot fMRI study.Journal of pain research · 2018Article
Corrections and comments
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Objectives Chronic gneck and shoulder pain (CNSP) is a common clinical symptom of cervical spondylotic radiculopathy. Several studies using resting-state functional magnetic resonance imaging (rs-fMRI) have reported that most chronic pain diseases are accompanied by structural and functional changes in the brain. However, few rs-fMRI studies have examined CNSP. The current study investigated cerebral structural and functional changes in CNSP patients. Methods In total, 25 CNSP patients and 20 healthy volunteers participated in the study. 3D-T1W and rs-fMRI images were acquired. Voxel-based morphometry analysis was applied to structural images, and regional homogeneity (ReHo) was extracted from rs-fMRI. Statistical analysis was performed on post-processing images and ReHo parameter maps. Results The results revealed no significant differences in brain structure between the two groups. In the patient group, ReHo values were significantly increased in the bilateral middle frontal gyrus and decreased in the left insula, superior frontal gyrus, middle cingulate gyrus, supplementary motor area, right postcentral gyrus, and superior parietal lobule. Conclusions This initial structural and rs-fMRI study of CNSP revealed characteristic features of spontaneous brain activity of CNSP patients. These findings may be helpful for increasing our understanding of the neuropathology of CNSP.
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