Evidence map›Paper›PMID 28222615›Full record

ArticleThe Journal of international medical research2016

Clinical associations, biological risk factors and outcomes of cerebral venous sinus thrombosis.

Hafize Nalan Gunes, Burcu Gokce Cokal, Selda Keskin Guler, Tahir Kurtulus Yoldas, Umit Yavuz Malkan, Cemile Sencer Demircan, Mehmet Ilker Yon, Zeynep Yoldas, Gursel Gunes, Ibrahim Celalettin Haznedaroglu

Open access · goldAbstract read
In one paragraph

Article in The Journal of international medical research, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed
2.5field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 55 citations in OpenAlex.

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  14. Cerebrovascular disease in women.Therapeutic advances in neurological disorders · 2021
    Review
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  19. Headache in cerebral venous thrombosis.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2020
    Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Hafize Nalan Gunes1 Department of Neurology, Ankara Training and Research Hospital, Ankara, Turkey.
Burcu Gokce Cokal1 Department of Neurology, Ankara Training and Research Hospital, Ankara, Turkey.
Selda Keskin Guler1 Department of Neurology, Ankara Training and Research Hospital, Ankara, Turkey.
Tahir Kurtulus Yoldas1 Department of Neurology, Ankara Training and Research Hospital, Ankara, Turkey.
Umit Yavuz Malkan2 Department of Hematology, Hacettepe University, Ankara, Turkey.
Cemile Sencer Demircan1 Department of Neurology, Ankara Training and Research Hospital, Ankara, Turkey.
Mehmet Ilker Yon1 Department of Neurology, Ankara Training and Research Hospital, Ankara, Turkey.
Zeynep Yoldas3 Zekai Tahir Burak Female Health Training and Research Hospital, Ankara, Turkey.
Gursel Gunes2 Department of Hematology, Hacettepe University, Ankara, Turkey.
Ibrahim Celalettin Haznedaroglu2 Department of Hematology, Hacettepe University, Ankara, Turkey.
Ministry of Health · TRHacettepe University · TRZekai Tahir Burak Kadın Sağlığı Eğitim ve Araştırma Hastanesi · TR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective Cerebral venous sinus thrombosis (CVST) is a rare cerebrovascular disease affecting young adults. The majority of the patients are female. The aim of this study is to assess the clinical associations, risk factors and outcomes of the patients with CVST. Methods The data of 75 patients with CVST admitted to our hospital between 2006 and 2016 were reviewed. Demographic and clinical features and the thrombophilic risk factors of the patients were recorded. The localizations of the thrombi were determined and modified Rankin score at the time of onset and discharge were calculated. Results The majority of our patients (78.7%) were female. Median age was 35 years (16-76). The most common symptom was headache (86.7%). In 82.6% of our patients, inherited or acquired risk factors for thrombosis were detected. Transverse sinus was the most common site of thrombosis followed by sigmoid and superior sagittal sinuses. Two thirds of the patients had involvement of multiple sinuses. The patients with the involvement of sagittal sinus had better disability at the time of admittance ( p = 0.013) while the number of involved sinuses was correlated worse disability ( p = 0.015). The neurologic states in the majority of the patients were improved by the end of the hospitalization period ( p = 0.001). There was no significant difference in disability score at discharge between men and women ( p = 0.080). No patient with CVST died in the hospitalization period. Conclusions This study is one of the largest cohort studies on CVST in our region. The results of the study disclosed that CVST had wide range of clinical manifestations and non-specific symptoms at the beginning. For that reason, in especially high risk groups for thrombosis, the diagnosis of CVST should be kept in mind.

Indexed as

AdolescentAdultAgedCohort StudiesFemaleHeadacheHumansLateral Sinus ThrombosisMaleMiddle AgedRisk FactorsSinus Thrombosis, IntracranialSuperior Sagittal SinusTreatment OutcomeVenous ThrombosisYoung AdultCerebral venous sinus thrombosisoutcomerisk factors

Identifiers

PMID28222615
PMCPMC5536748
OpenAlexW2554274722

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.