Evidence map›Paper›PMID 28222379›Full record

Trial reportRedox biology2017

Increased static and decreased capacity oxidation-reduction potentials in plasma are predictive of metabolic syndrome.

Gerd Bobe, Tora J Cobb, Scott W Leonard, Savinda Aponso, Christopher B Bahro, Dipankar Koley, Eunice Mah, Richard S Bruno, Maret G Traber

Open access · goldAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Redox biology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
2.3field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 31 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Gerd BobeLinus Pauling Institute, Oregon State University, Corvallis, OR 97331, United States.
Tora J CobbLinus Pauling Institute, Oregon State University, Corvallis, OR 97331, United States.
Scott W LeonardLinus Pauling Institute, Oregon State University, Corvallis, OR 97331, United States.
Savinda AponsoDepartment of Chemistry, Oregon State University, Corvallis, OR 97331, United States.
Christopher B BahroDepartment of Chemistry, Oregon State University, Corvallis, OR 97331, United States.
Dipankar KoleyDepartment of Chemistry, Oregon State University, Corvallis, OR 97331, United States.
Eunice MahBiofortis, Inc., Addison, IL, United States.
Richard S BrunoHuman Nutrition Program, The Ohio State University, Columbus, OH 43210, United States.
Maret G TraberLinus Pauling Institute, Oregon State University, Corvallis, OR 97331, United States. Electronic address: maret.traber@oregonstate.edu.
Oregon State University · USThe Ohio State University · US

Funding

The Ohio State University Center for clinical and Translational ScienceUL1TR001070 · NCATS · OHIO STATE UNIVERSITY · PI JACKSON, REBECCA D · 2013 to 2017
$22.6M
Vitamin E Requirements in Women,Obese Women and Diabetic Obese WomenR01DK081761 · NIDDK · OREGON STATE UNIVERSITY · PI TRABER, MARET G · 2010 to 2014
$1.8M
NCATS NIH HHS UL1 TR001070NIDDK NIH HHS R01 DK081761
6 · The paper itself

Abstract

Electric conductivity in plasma is the balance between oxidized and reduced molecules (static Oxidation-Reduction Potential, sORP) and the amount of readily oxidizable molecules (capacity ORP, cORP). Adults with metabolic syndrome (MetS) have increased inflammation, dyslipidemia and oxidative stress; therefore, participants with MetS were hypothesized to have higher plasma sORP and lower cORP than those measures in healthy adults. Heparin-anticoagulated plasma from healthy and age- and gender-matched individuals with MetS (BMI: 22.6±0.7 vs. 37.7±3.0kg/m

Indexed as

Oxidation-ReductionAdultBiomarkersCholesterol, HDLC-Reactive ProteinCross-Over StudiesDouble-Blind MethodFemaleHumansInterleukin-10Lipoproteins, LDLMaleMetabolic SyndromeTriglyceridesYoung AdultBiomarkersCholesterol, HDLC-Reactive ProteinIL10 protein, humanInterleukin-10Lipoproteins, LDLTriglyceridesDyslipidemiaInflammationIsoprostanesLipid peroxidationMetabolic syndromeObesityOxidation-reduction potential

Identifiers

PMID28222379
PMCPMC5318349
OpenAlexW2588584000

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.