ReviewJournal of perinatal medicine2017
Evidence-based, ethically justified counseling for fetal bilateral renal agenesis.
Review in Journal of perinatal medicine, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
14 citing papers in PubMed, 35 citations in OpenAlex.
- Fetal Multicystic Dysplastic Kidney and Its Effect on Post-natal Quality of Life: A Literature Review.Cureus · 2026Review
- Recent progress in xenotransplantation and its application to pediatric kidney disease.Pediatric nephrology (Berlin, Germany) · 2025Review
- A surveillance-based epidemiological study of renal agenesis in 25 million births in china, 2007-2020.BMC pregnancy and childbirth · 2025Article
- Fetal-to-fetal kidney transplantation in utero.Communications biology · 2025Article
- Bilateral renal agenesis: fetal intervention and outcomes.Pediatric nephrology (Berlin, Germany) · 2025Review
- Comparison of Serial Amnioinfusion Strategies for Isolated Early-Onset Fetal Renal Anhydramnios.Fetal diagnosis and therapy · 2025Article
- Prenatally-diagnosed renal failure: an ethical framework for decision-making.Journal of perinatology : official journal of the California Perinatal Association · 2024Review
- Achievements, priorities and strategies in pediatric nephrology in Europe: need for unifying approaches or acceptance of differences?Frontiers in pediatrics · 2024Article
- Design and Protocol of the Renal Anhydramnios Fetal Therapy (RAFT) Trial.Clinical therapeutics · 2022Article
- Fetal interventions for congenital renal anomalies.Translational pediatrics · 2021Review
- Influence of Religiosity on Situational Coping Scores in Women with Malformed Fetuses.Journal of religion and health · 2020Article
- Discordance for Potter's Syndrome in a Dichorionic Diamniotic Twin Pregnancy-An Unusual Case Report.Medicina (Kaunas, Lithuania) · 2020Article
- End-stage kidney disease in infancy: an educational review.Pediatric nephrology (Berlin, Germany) · 2020Review
- Prenatal genetic considerations of congenital anomalies of the kidney and urinary tract (CAKUT).Prenatal diagnosis · 2019Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 2 institutions in 1 country.
Funding
Abstract
backgroundNot much data are available on the natural history of bilateral renal agenesis, as the medical community does not typically offer aggressive obstetric or neonatal care asbilateral renal agenesis has been accepted as a lethal condition.
aimTo provide an evidence-based, ethically justified approach to counseling pregnant women about the obstetric management of bilateral renal agenesis. STUDY
designA systematic literature search was performed using multiple databases. We deploy an ethical analysis of the results of the literature search on the basis of the professional responsibility model of obstetric ethics.
resultsEighteen articles met the inclusion criteria for review. With the exception of a single case study using serial amnioinfusion, there has been no other case of survival following dialysis and transplantation documented. Liveborn babies die during the neonatal period. Counseling pregnant women about management of pregnancies complicated by bilateral renal agenesis should be guided by beneficence-based judgment informed by evidence about outcomes.
conclusionsBased on the ethical analysis of the results from this review, without experimental obstetric intervention, neonatal mortality rates will continue to be 100%. Serial amnioinfusion therefore should not be offered as treatment, but only as approved innovation or research.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.