Trial reportJournal of the American Geriatrics Society2017
Effect of Physical Activity versus Health Education on Physical Function, Grip Strength and Mobility.
Trial report in Journal of the American Geriatrics Society, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 44 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
44 citing papers in PubMed, 2 syntheses or guidelines pooled it, 105 citations in OpenAlex.
- Comparison of Power Training vs Traditional Strength Training on Physical Function in Older Adults: A Systematic Review and Meta-analysis.JAMA network open · 2022Pooled it
- Exercise-Based Interventions to Enhance Long-Term Sustainability of Physical Activity in Older Adults: A Systematic Review and Meta-Analysis of Randomized Clinical Trials.International journal of environmental research and public health · 2019Pooled it
- Effect of HY7602-Fermented Deer Antler Extract on Selected Muscle-Related Outcomes and Fermentation-Associated Metabolomic Profiles.Journal of microbiology and biotechnology · 2026Trial
- A high intensity vs. casual speed walking intervention to reverse frailty among older adults: a cluster randomized controlled trial.PloS one · 2026Trial
- Effect of resistance training on physical function during chemotherapy in colon cancer.JNCI cancer spectrum · 2024Trial
- Biomarkers of Cellular Senescence Predict the Onset of Mobility Disability and Are Reduced by Physical Activity in Older Adults.The journals of gerontology. Series A, Biological sciences and medical sciences · 2024Trial
- Agility performance in healthy older adults is associated with handgrip strength and force development: results from a 1-year randomized controlled trial.European geriatric medicine · 2023Trial
- Integrating a physical activity coaching intervention into diabetes care: a mixed-methods evaluation of a pilot pragmatic trial.Translational behavioral medicine · 2022Trial
- Metabolic syndrome and the benefit of a physical activity intervention on lower-extremity function: Results from a randomized clinical trial.Experimental gerontology · 2021Trial
- A Pilot Randomised Clinical Trial of a Novel Approach to Reduce Sedentary Behaviour in Care Home Residents: Feasibility and Preliminary Effects of the GET READY Study.International journal of environmental research and public health · 2020Trial
- Feasibility Trial Evaluation of a Peer Volunteering Active Aging Intervention: ACE (Active, Connected, Engaged).The Gerontologist · 2020Trial
- Progressive Resistance Training Improves Torque Capacity and Strength in Mobility-Limited Older Adults.The journals of gerontology. Series A, Biological sciences and medical sciences · 2019Trial
- PRIME: A Novel Low-Mass, High-Repetition Approach to Improve Function in Older Adults.Medicine and science in sports and exercise · 2018Trial
- Mediating role of frailty/pre-frailty on the association between exercise participation and traffic crashes among Japanese community-dwelling older drivers.BMC geriatrics · 2025Article
- Efficacy of a Wearable Activity Tracker With Step-by-Step Goal-Setting on Older Adults' Physical Activity and Sarcopenia Indicators: Clustered Trial.Journal of medical Internet research · 2024Article
- Mobility Abilities Mediate the Association of a More Active Lifestyle With Mobility Disability in Older Adults.The journals of gerontology. Series A, Biological sciences and medical sciences · 2024Article
- Association between wrist-worn free-living accelerometry and hand grip strength in middle-aged and older adults.Aging clinical and experimental research · 2024Article
- Effect of Different Exercise Interventions on Grip Strength, Knee Extensor Strength, Appendicular Skeletal Muscle Index, and Skeletal Muscle Index Strength in Patients with Sarcopenia: A Meta-Analysis of Randomized Controlled Trials.Diseases (Basel, Switzerland) · 2024Review
- Evaluating individual level change in physical function response following an exercise program for cancer survivors.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2023Article
- The mediating effect of leisure activities in the relationship between depression and cognitive decline in middle age and older adults in Taiwan.BMC geriatrics · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
17 authors at 10 institutions in 1 country.
Funding
Abstract
backgroundPhysical activity (PA) reduces the rate of mobility disability, compared with health education (HE), in at risk older adults. It is important to understand aspects of performance contributing to this benefit.
objectiveTo evaluate intervention effects on tertiary physical performance outcomes.
designThe Lifestyle Interventions and Independence for Elders (LIFE) was a multi-centered, single-blind randomized trial of older adults.
settingEight field centers throughout the United States.
participants1635 adults aged 78.9 ± 5.2 years, 67.2% women at risk for mobility disability (Short Physical Performance Battery [SPPB] <10).
interventionsModerate PA including walking, resistance and balance training compared with HE consisting of topics relevant to older adults. OUTCOMES: Grip strength, SPPB score and its components (balance, 4 m gait speed, and chair-stands), as well as 400 m walking speed.
resultsTotal SPPB score was higher in PA versus HE across all follow-up times (overall P = .04) as was the chair-stand component (overall P < .001). No intervention effects were observed for balance (overall P = .12), 4 m gait speed (overall P = .78), or grip strength (overall P = .62). However, 400 m walking speed was faster in PA versus HE group (overall P =<.001). In separate models, 29% of the rate reduction of major mobility disability in the PA versus HE group was explained by change in SPPB score, while 39% was explained by change in the chair stand component.
conclusionLower extremity performance (SPPB) was significantly higher in the PA compared with HE group. Changes in chair-stand score explained a considerable portion of the effect of PA on the reduction of major mobility disability-consistent with the idea that preserving muscle strength/power may be important for the prevention of major mobility disability.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.