ArticleJournal of clinical laboratory analysis2018
More significance of TB-IGRA except for the diagnose of tuberculosis.
Article in Journal of clinical laboratory analysis, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
10 citing papers in PubMed, 15 citations in OpenAlex.
- Metagenomic next-generation sequencing for tuberculosis diagnosis: enhanced performance and cost-effectiveness.Microbiology spectrum · 2026Observational
- Evaluation of Immunogenicity ofVaccines · 2025Article
- Comparative Performance of Ante-Mortem Diagnostic Assays for the Identification ofPathogens (Basel, Switzerland) · 2025Article
- The changes and its significance of peripheral blood NK cells in patients with tuberculous meningitis.Frontiers in microbiology · 2024Article
- The exhaustion of lymphocytes is the main factor that decreases the sensitivity of QFT-GIT detection in silicosis.BMC immunology · 2022Article
- Algorithm Design for a Cytokine Release Assay of Antigen-Specific In Vitro Stimuli of Circulating Leukocytes to Classify Leprosy Patients and Household Contacts.Open forum infectious diseases · 2022Article
- Mesenchymal Stem Cells and Tuberculosis: Clinical Challenges and Opportunities.Frontiers in immunology · 2021Review
- Combining interferon-The Journal of international medical research · 2020Observational
- Clinical effect of T-SPOT.TB test for the diagnosis of tuberculosis.BMC infectious diseases · 2019Article
- More significance of TB-IGRA except for the diagnose of tuberculosis.Journal of clinical laboratory analysis · 2018Article
Corrections and comments
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Authors and funding
10 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTuberculosis (TB)-interferon gamma release assay (IGRA) test has the characteristics of short time, high specificity, and high sensitivity, but it lacks the correlation research between TB-IGRA test results and body's immune cells, disease progression and prognosis, which is explored in this study.
designA retrospective study was carried out on positive TB-IGRA patients who were infected with TB and diagnosed at our hospital from January 2014 to June 2015. The TB-IGRA, routine blood test, T-cell subgroup data were collected for statistical analysis.
resultsTB-IGRA results were in positive proportion to the lymphocytes, CD4
conclusionsIFN-γ was tested with TB-IGRA in patients with TB by the specific TB T cells and correlated with the lymphocytes, while the lymphocytes also closely related to the host's anti-TB immunity and disease outcome. Hence the result of TB-IGRA could reflect the specific anti-TB immunity ability of the host, disease progression and prognosis. This study further expands the application scope of TB-IGRA technology in the diagnosis of TB and lays a foundation for clinical practice to understand the immunity state of the patients with TB and the application of auxiliary clinical immunity regulators.
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Registered trials
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