Evidence map›Paper›PMID 28220834›Full record

ArticleScientific reports2017

Stellera chamaejasme and its constituents induce cutaneous wound healing and anti-inflammatory activities.

Myungsuk Kim, Hee Ju Lee, Ahmad Randy, Ji Ho Yun, Sang-Rok Oh, Chu Won Nho

Abstract read
In one paragraph

Article in Scientific reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Enhanced Skin-Protective Effects of a NovelJournal of microbiology and biotechnology · 2025
    Article
  2. Article
  3. Article
  4. Terpenoids from the Roots ofMolecules (Basel, Switzerland) · 2023
    Article
  5. Antioxidant and Anti-Inflammatory Activities ofLife (Basel, Switzerland) · 2023
    Article
  6. Characterization of Polyphenolic Compounds fromMolecules (Basel, Switzerland) · 2022
    Article
  7. Gel formulated withFrontiers in pharmacology · 2022
    Article
  8. Review
  9. Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society · 2019
    Article
  10. Article
  11. Exploring Chemical Basis of Toxicity Reduction for Processed Roots ofInternational journal of analytical chemistry · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Myungsuk KimNatural Products Research Center, Korea Institute of Science and Technology, Gangneung, Republic of Korea.
Hee Ju LeeSystems Biotechnology Research Center, Korea Institute of Science and Technology, Gangneung, Republic of Korea.
Ahmad RandyNatural Products Research Center, Korea Institute of Science and Technology, Gangneung, Republic of Korea.
Ji Ho YunNatural Products Research Center, Korea Institute of Science and Technology, Gangneung, Republic of Korea.
Sang-Rok OhConvergence Research Center for Smart Farm Solution, Korea Institute of Science and Technology, Gangneung, Republic of Korea.
Chu Won NhoNatural Products Research Center, Korea Institute of Science and Technology, Gangneung, Republic of Korea.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Stellera chamaejasme L. (Thymelaeaceae) is a perennial herb that is widely used in traditional Chinese medicine to treat tumours, tuberculosis and psoriasis. S. chamaejasme extract (SCE) possesses anti-inflammatory, analgesic and wound healing activities; however, the effect of S. chamaejasme and its active compounds on cutaneous wound healing has not been investigated. We assessed full-thickness wounds of Sprague-Dawley (SD) rats and topically applied SCE for 2 weeks. In vitro studies were performed using HaCaT keratinocytes, Hs68 dermal fibroblasts and RAW 264.7 macrophages to determine cell viability (MTT assay), cell migration, collagen expression, nitric oxide (NO) production, prostaglandin E

Indexed as

AnimalsAnti-Inflammatory AgentsCell LineChromatography, LiquidCollagenExtracellular Signal-Regulated MAP KinasesHumansInflammation MediatorsMacrophagesMagnetic Resonance SpectroscopyMass SpectrometryMiceMolecular StructureOncogene Protein v-aktPhytochemicalsPlant ExtractsAnti-Inflammatory AgentsCollagenExtracellular Signal-Regulated MAP KinasesInflammation MediatorsOncogene Protein v-aktPhytochemicalsPlant Extracts

Identifiers

PMID28220834
PMCPMC5318992

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.