ArticleSpinal cord2017
Pulmonary outcomes following specialized respiratory management for acute cervical spinal cord injury: a retrospective analysis.
Article in Spinal cord, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
21 citing papers in PubMed, 40 citations in OpenAlex.
- Correlation of diaphragmatic ultrasound with pulmonary function testing in patients with chronic cervical spinal cord injury: A single center pilot study.The journal of spinal cord medicine · 2026Article
- A perioperative predictive model of early mortality in acute cervical spinal cord injury: A prospective cohort study.Journal of clinical orthopaedics and trauma · 2024Article
- Sex hormone supplementation improves breathing and restores respiratory neuroplasticity following C2 hemisection in rats.Frontiers in physiology · 2024Article
- Review
- A Comprehensive Spinal Cord Injury Treatment Protocol Improves Outcomes and Decreases Complications.The American surgeon · 2023Article
- Association between Anterior Surgical Approach and Dysphagia Severity in Patients with Cervical Spinal Cord Injury.Journal of clinical medicine · 2023Article
- Respiratory Complications and Weaning Considerations for Patients with Spinal Cord Injuries: A Narrative Review.Journal of personalized medicine · 2022Review
- Respiratory plasticity following spinal cord injury: perspectives from mouse to man.Neural regeneration research · 2022Review
- Successful decannulation of patients with traumatic spinal cord injury: A scoping review.The journal of spinal cord medicine · 2022Article
- A Nomogram for Predicting Acute Respiratory Failure After Cervical Traumatic Spinal Cord Injury Based on Admission Clinical Findings.Neurocritical care · 2022Article
- Utilizing Pulmonary Function Parameters to Predict Dysphagia in Individuals With Cervical Spinal Cord Injuries.Annals of rehabilitation medicine · 2021Article
- Separation from mechanical ventilation and survival after spinal cord injury: a systematic review and meta-analysis.Annals of intensive care · 2021Review
- Respiratory morbidity and mortality of traumatic cervical spinal cord injury at a level I trauma center in India.Spinal cord series and cases · 2021Article
- Initial assessment and management of respiratory infections in persons with spinal cord injuries and disorders in the COVID-19 era.Journal of the American College of Emergency Physicians open · 2020Review
- Data Dissemination: Shortening the Long Tail of Traumatic Brain Injury Dark Data.Journal of neurotrauma · 2020Review
- Practical approach to respiratory emergencies in neurological diseases.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2020Review
- Exploration of surgical blood pressure management and expected motor recovery in individuals with traumatic spinal cord injury.Spinal cord · 2020Article
- A Review of Different Stimulation Methods for Functional Reconstruction and Comparison of Respiratory Function after Cervical Spinal Cord Injury.Applied bionics and biomechanics · 2020Review
- Rho Inhibitor VX-210 in Acute Traumatic Subaxial Cervical Spinal Cord Injury: Design of the SPinal Cord Injury Rho INhibition InvestiGation (SPRING) Clinical Trial.Journal of neurotrauma · 2018Article
- Observational
Corrections and comments
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Authors and funding
6 authors at 4 institutions in 1 country.
Funding
Abstract
STUDY
designRetrospective analysis.
objectivesTo identify multivariate interactions of respiratory function that are sensitive to spinal cord injury level and pharmacological treatment to promote strategies that increase successful liberation from mechanical ventilation.
settingUnited States regional spinal cord injury (SCI) treatment center.
methodsRetrospective chart review of patients consecutively admitted to Santa Clara Valley Medical Center between May 2013 and December 2014 for ventilator weaning with C1-C5 American Spinal Injury Association Impairment Scale (AIS) A or B SCI, <3 months from injury and who had a tracheostomy in place. A nonlinear, categorical principal component analysis (NL-PCA) was performed to test the multivariate interaction of respiratory outcomes from patients (N=36) being weaned off ventilator support after acute SCI with (N=15) or without (N=21) theophylline treatment.
resultsIn total, 36 patients met inclusion criteria (2 C1, 5 C2, 11 C3, 14 C4 and 4 C5). The NL-PCA returned three independent components that accounted for 95% of the variance in the data set. Multivariate general linear models hypothesis tests revealed a significant syndromic interaction between theophylline treatment and SCI level (Wilks' Lambda, P=0.028, F (12,64)=2.116, η
conclusionsWe suspect that some portion of the high success rate of ventilator weaning may be attributable to theophylline use in higher cervical SCI, in addition to our aggressive regimen of high volume ventilation, medication optimization and pulmonary toilet (positive pressure treatments and mechanical insufflation-exsufflation).
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