Evidence map›Paper›PMID 28220820›Full record

ArticleSpinal cord2017

Testicular responses to hCG stimulation at varying doses in men with spinal cord injury.

W A Bauman, M F La Fountaine, C M Cirnigliaro, S C Kirshblum, A M Spungen

Abstract read
In one paragraph

Article in Spinal cord, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Trial
  2. Factors affecting sexual health in individuals with spinal cord injury: A systematic scoping review.Chinese journal of traumatology = Zhonghua chuang shang za zhi · 2025
    Article
  3. Review
  4. Article
  5. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

W A BaumanDepartment of Veterans Affairs Rehabilitation Research &Development Service National Center for the Medical Consequences of Spinal Cord Injury, James J Peters Veterans Affairs Medical Center, Bronx, NY, USA.
M F La FountaineDepartment of Veterans Affairs Rehabilitation Research &Development Service National Center for the Medical Consequences of Spinal Cord Injury, James J Peters Veterans Affairs Medical Center, Bronx, NY, USA.
C M CirnigliaroDepartment of Veterans Affairs Rehabilitation Research &Development Service National Center for the Medical Consequences of Spinal Cord Injury, James J Peters Veterans Affairs Medical Center, Bronx, NY, USA.
S C KirshblumKessler Institute for Rehabilitation, West Orange, NJ, USA.
A M SpungenDepartment of Veterans Affairs Rehabilitation Research &Development Service National Center for the Medical Consequences of Spinal Cord Injury, James J Peters Veterans Affairs Medical Center, Bronx, NY, USA.

Funding

National Center on Medical Consequences of Spinal Cord InjuryI50RX002020 · VA · JAMES J PETERS VA MEDICAL CENTER · PI BAUMAN, WILLIAM A, SPUNGEN, ANN MICHELE · 2016 to 2020
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RRD VA B9212-CRRD VA I50 RX002020
6 · The paper itself

Abstract

STUDY

designProspective.

objectivesTo test whether provocative stimulation of the testes identifies men with chronic spinal cord injury (SCI), a population in which serum testosterone concentrations are often depressed, possibly due to gonadal dysfunction. To accomplish this objective, conventional and lower than the conventional doses of human chorionic gonadotropin (hCG) were administered.

methodsThirty men with chronic SCI (duration of injury >1 year; 18 and 65 years old; 16 eugonadal (>12.1 nmol l

resultsThe average gonadal response in the SCI and AB groups to each dose of hCG was not significantly different in the hypogonadal or eugonadal subjects, with the mean serum testosterone concentrations in all groups demonstrating an adequate response.

conclusionsThis work confirmed the absence of primary testicular dysfunction without additional benefit demonstrated of provocative stimulation of the testes with lower than conventional doses of hCG. Our findings support prior work that suggested a secondary testicular dysfunction that occurs in a majority of those with SCI and depressed serum testosterone concentrations.

Indexed as

AdolescentAdultAgedChorionic GonadotropinDose-Response Relationship, DrugHumansHypogonadismInjections, IntramuscularMaleMiddle AgedProspective StudiesSpinal Cord InjuriesTestisTestosteroneYoung AdultChorionic GonadotropinTestosterone

Identifiers

PMID28220820
PMCPMC5501758

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.