Evidence map›Paper›PMID 28220797›Full record

ArticleNeuropsychopharmacology : official publication of the American College of Neuropsychopharmacology2017

Elevated Choline-Containing Compound Levels in Rapid Cycling Bipolar Disorder.

Bo Cao, Jeffrey A Stanley, Ives Cavalcante Passos, Benson Mwangi, Sudhakar Selvaraj, Giovana B Zunta-Soares, Jair C Soares

Open access · bronzeAbstract read
In one paragraph

Article in Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 2 pooled it
0.7field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 2 syntheses or guidelines pooled it, 17 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Observational
  4. Article
  5. Article
  6. Review
  7. Article
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Bo CaoDepartment of Psychiatry and Behavioral Sciences, The University of Texas Health Science Center at Houston, TX, USA.
Jeffrey A StanleyDepartment of Psychiatry &Behavioral Neurosciences, School of Medicine, Wayne State University, Detroit, MI, USA.
Ives Cavalcante PassosGraduation Program in Psychiatry and Department of Psychiatry, Universidade Federal do Rio Grande do Sul (UFRGS), Porto Alegre (RS), Brazil.
Benson MwangiDepartment of Psychiatry and Behavioral Sciences, The University of Texas Health Science Center at Houston, TX, USA.
Sudhakar SelvarajDepartment of Psychiatry and Behavioral Sciences, The University of Texas Health Science Center at Houston, TX, USA.
Giovana B Zunta-SoaresDepartment of Psychiatry and Behavioral Sciences, The University of Texas Health Science Center at Houston, TX, USA.
Jair C SoaresDepartment of Psychiatry and Behavioral Sciences, The University of Texas Health Science Center at Houston, TX, USA.
The University of Texas Health Science Center at Houston · USUniversidade Federal do Rio Grande do Sul · BRWayne State University · US

Funding

Searching for Endophenotypes of Bipolar DisorderR01MH085667 · NIMH · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI SOARES, JAIR C · 2012 to 2016
$3.0M
NIMH NIH HHS R01 MH085667
6 · The paper itself

Abstract

Previous studies have found increased levels of choline-containing compounds (ie, glycerophosphocholine plus phosphocholine (GPC+PC)) in bipolar disorder using in vivo proton magnetic resonance spectroscopy (

Indexed as

AdolescentAdultAgedBipolar DisorderBrainFemaleGlycerylphosphorylcholineHumansLinear ModelsMaleMiddle AgedPhosphorylcholineProton Magnetic Resonance SpectroscopyPsychiatric Status Rating ScalesYoung AdultGlycerylphosphorylcholinePhosphorylcholine

Identifiers

PMID28220797
PMCPMC5603812
OpenAlexW2589790718

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.