Evidence map›Paper›PMID 28220506›Full record

ArticleResearch in nursing & health2017

Network Structure of Perinatal Depressive Symptoms in Latinas: Relationship to Stress and Reproductive Biomarkers.

Hudson Santos, Eiko I Fried, Josephine Asafu-Adjei, R Jeanne Ruiz

Abstract read
In one paragraph

Article in Research in nursing & health, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 55 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
55citing papers in PubMed, 3 pooled it
11.4field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

55 citing papers in PubMed, 3 syntheses or guidelines pooled it, 122 citations in OpenAlex.

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  19. Major depressive episode and postpartum depression: A network analysis comparison on the IGEDEPP cohort.European psychiatry : the journal of the Association of European Psychiatrists · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 2 countries.

Hudson SantosSchool of Nursing, The University of North Carolina at Chapel Hill, Carrington Hall, CB# 7460 Chapel Hill, NC 27599.ORCID http://orcid.org/0000-0002-4040-366X
Eiko I FriedUniversity of Amsterdam, Amsterdam, Netherlands.
Josephine Asafu-AdjeiThe University of North Carolina at Chapel Hill, Chapel Hill, NC.
R Jeanne RuizTexas A&M Health Science Center, Bryan, TX.
University of North Carolina at Chapel Hill · USAmsterdam University of the Arts · NLTexas A&M Health Science Center · US

Funding

Re-Entry Supplement: Investigation of Oral Microbial Enzymes for the Detection and Treatment of Periodontal DiseaseUL1TR002489 · NCATS · UNIV OF NORTH CAROLINA CHAPEL HILL · PI BUSE, JOHN BERNARD, SHAHEEN, NICHOLAS J · 2018 to 2022
$48.6M
North Carolina Translational & Clinical Sciences Institute (NC TraCS)UL1TR001111 · NCATS · UNIV OF NORTH CAROLINA CHAPEL HILL · PI BUSE, JOHN BERNARD, CAREY, TIMOTHY S · 2013 to 2017
$43.9M
Psychoneuroimmunology: Preterm birth in HispanicsR01NR007891 · NINR · UNIVERSITY OF TEXAS MEDICAL BR GALVESTON · PI RUIZ, ROBERTA JEANNE · 2002 to 2011
$3.9M
NCATS NIH HHS UL1 TR001111NCATS NIH HHS UL1 TR002489NINR NIH HHS R01 NR007891
6 · The paper itself

Abstract

Based on emerging evidence, mood disorders can be plausibly conceptualized as networks of causally interacting symptoms, rather than as latent variables of which symptoms are passive indicators. In an innovative approach in nursing research, we used network analysis to estimate the network structure of 20 perinatal depressive (PND) symptoms. Then, two proof-of-principle analyses are presented: Incorporating stress and reproductive biomarkers into the network, and comparing the network structure of PND symptoms between non-depressed and depressed women. We analyzed data from a cross-sectional sample of 515 Latina women at the second trimester of pregnancy and estimated networks using regularized partial correlation network models. The main analysis yielded five strong symptom-to-symptom associations (e.g., cry-sadness), and five symptoms of potential clinical importance (i.e., high centrality) in the network. In exploring the relationship of PND symptoms to stress and reproductive biomarkers (proof-of-principle analysis 1), a few weak relationships were found. In a comparison of non-depressed and depressed women's networks (proof-of-principle analysis 2), depressed participants had a more connected network of symptoms overall, but the networks did not differ in types of relationships (the network structures). We hope this first report of PND symptoms as a network of interacting symptoms will encourage future network studies in the realm of PND research, including investigations of symptom-to-biomarker mechanisms and interactions related to PND. Future directions and challenges are discussed. © 2017 Wiley Periodicals, Inc.

Indexed as

Perinatal CareSymptom AssessmentAdultBiomarkersCross-Sectional StudiesDepressionFemaleHispanic or LatinoHumansNursing ResearchPregnancyPregnancy Trimester, SecondStress, PsychologicalBiomarkersbiomarkersdepressive symptomsLatinasnetwork analysisperinatal depression

Identifiers

PMID28220506
PMCPMC5503306
OpenAlexW2590066559

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.