Evidence map›Paper›PMID 28220358›Full record

ArticleJournal of autism and developmental disorders2017

Potential Risk Factors for the Development of Self-Injurious Behavior among Infants at Risk for Autism Spectrum Disorder.

Adele F Dimian, Kelly N Botteron, Stephen R Dager, Jed T Elison, Annette M Estes, John R Pruett, Robert T Schultz, Lonnie Zwaigenbaum, Joseph Piven, Jason J Wolff and 1 more

Open access · hybridAbstract readMulticenter Study
In one paragraph

Article in Journal of autism and developmental disorders, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
1.6field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it, 30 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Predictors of Change in Severity of Self-Injurious Behaviors in Preschool-Aged Autistic Children.Autism research : official journal of the International Society for Autism Research · 2026
    Article
  4. Review
  5. Article
  6. Review
  7. Article
  8. Review
  9. Article
  10. Cataloguing and characterizing interests in typically developing toddlers and toddlers who develop ASD.Autism research : official journal of the International Society for Autism Research · 2021
    Article
  11. Article
  12. Article
  13. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 2 countries.

Adele F DimianDepartment of Educational Psychology, University of Minnesota, 56 East River Rd., Minneapolis, MN, 55455, USA.
Kelly N BotteronDepartment of Psychiatry, Washington University in St. Louis, St. Louis, MO, USA.
Stephen R DagerDepartment of Radiology, University of Washington, Seattle, WA, USA.
Jed T ElisonInstitute of Child Development, University of Minnesota, Minneapolis, MN, USA.
Annette M EstesDepartment of Speech and Hearing Sciences, University of Washington, Seattle, WA, USA.
John R PruettDepartment of Psychiatry, Washington University in St. Louis, St. Louis, MO, USA.
Robert T SchultzCenter for Autism Research, Children's Hospital of Philadelphia, Philadelphia, PA, USA.
Lonnie ZwaigenbaumDepartment of Pediatrics, University of Alberta, Edmonton, AB, Canada.
Joseph PivenDepartment of Psychiatry, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
Jason J WolffDepartment of Educational Psychology, University of Minnesota, 56 East River Rd., Minneapolis, MN, 55455, USA. jjwolff@umn.edu.ORCID 0000-0003-4300-8195
IBIS Network
University of Minnesota · USChildren's Hospital of Philadelphia · USUniversity of North Carolina at Chapel Hill · USUniversity of Washington · US

Funding

UNC-CH CENTER FOR ENVIRONMENTAL HEALTH &SUSCEPTIBILITYP30ES010126 · NIEHS · UNIV OF NORTH CAROLINA CHAPEL HILL · PI Melissa A. Troester · 2001 to 2026
$36.3M
UNC MRDD Research CenterP30HD003110 · NICHD · UNIV OF NORTH CAROLINA CHAPEL HILL · PI BELGER, AYSENIL · 1985 to 2012
$28.7M
Intellectual and Developmental Disabilities Research CenterU54HD083091 · NICHD · UNIVERSITY OF WASHINGTON · PI DOHERTY, DANIEL · 2014 to 2019
$7.9M
Washington University Intellectual and Developmental Disabilities Research Center-Administrative Down Syndrome SupplementU54HD087011 · NICHD · WASHINGTON UNIVERSITY · PI MOLEY, KELLE H · 2015 to 2019
$7.1M
The Intellectual and Developmental Disabilities Research Center at CHOP/PennU54HD086984 · NICHD · CHILDREN'S HOSP OF PHILADELPHIA · PI PUTT, MARY E. · 2016 to 2020
$6.3M
Brain Imaging Markers of Response to Intervention in Toddlers with AutismK01MH101653 · NIMH · UNIV OF NORTH CAROLINA CHAPEL HILL · PI WOLFF, JASON J · 2013 to 2017
$651k
NICHD NIH HHS P30 HD003110NICHD NIH HHS U54 HD083091NICHD NIH HHS U54 HD086984NICHD NIH HHS U54 HD087011NIEHS NIH HHS P30 ES010126NIMH NIH HHS K01 MH101653
6 · The paper itself

Abstract

Prevalence of self-injurious behavior (SIB) is as high as 50% among children with autism spectrum disorder (ASD). Identification of risk factors for the development of SIB is critical to early intervention and prevention. However, there is little empirical research utilizing a prospective design to identify early risk factors for SIB. The purpose of this study was to evaluate behavioral characteristics predicting SIB at age 2 years among 235 infants at high familial risk for ASD. Logistic regression results indicated that presence of SIB or proto-SIB and lower developmental functioning at age 12 months significantly predicted SIB at 24 months. A pattern of persistent SIB over this period was associated with a diagnosis of autism and poorer cognitive and adaptive outcomes.

Indexed as

Autism Spectrum DisorderChild DevelopmentChild, PreschoolDevelopmental DisabilitiesFemaleHumansInfantLogistic ModelsLongitudinal StudiesMalePrevalenceProspective StudiesRisk FactorsSelf-Injurious BehaviorAutism spectrum disorderInfantsRepetitive behaviorRisk factorsSelf-injurious behavior

Identifiers

PMID28220358
PMCPMC5385192
OpenAlexW2589359879

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.