Evidence map›Paper›PMID 28220081›Full record

ArticleFrontiers in physiology2017

Muscles Susceptibility to Ischemia-Reperfusion Injuries Depends on Fiber Type Specific Antioxidant Level.

Anne-Laure Charles, Anne-Sophie Guilbert, Max Guillot, Samy Talha, Anne Lejay, Alain Meyer, Michel Kindo, Valérie Wolff, Jamal Bouitbir, Joffrey Zoll and 1 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in physiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers.

0numbers the graph read from it
0cells of the map it votes in
35citing papers in PubMed
4.6field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

35 citing papers in PubMed, 56 citations in OpenAlex.

  1. Article
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  5. Traumatic Skeletal Muscle Injury and Recovery.Advances in experimental medicine and biology · 2025
    Review
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  20. Preconditioning improves muscle regeneration after ischemia-reperfusion injury.Journal of orthopaedic research : official publication of the Orthopaedic Research Society · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 2 countries.

Anne-Laure CharlesEquipe d'accueil 3072, Faculté de Médecine, Fédération de Médecine Translationnelle, Université de StrasbourgStrasbourg, France; Service de Physiologie et d'Explorations Fonctionnelles, Pôle de Pathologie Thoracique, Nouvel Hôpital Civil, CHRU de StrasbourgStrasbourg, France.
Anne-Sophie GuilbertEquipe d'accueil 3072, Faculté de Médecine, Fédération de Médecine Translationnelle, Université de StrasbourgStrasbourg, France; Service de Réanimation Médico-Chirurgicale Pédiatrique Spécialisée, Hôpital de Hautepierre, CHRU de StrasbourgStrasbourg, France.
Max GuillotEquipe d'accueil 3072, Faculté de Médecine, Fédération de Médecine Translationnelle, Université de StrasbourgStrasbourg, France; Service de Réanimation Médicale, Hôpital de Hautepierre, CHRU de StrasbourgStrasbourg, France.
Samy TalhaEquipe d'accueil 3072, Faculté de Médecine, Fédération de Médecine Translationnelle, Université de StrasbourgStrasbourg, France; Service de Physiologie et d'Explorations Fonctionnelles, Pôle de Pathologie Thoracique, Nouvel Hôpital Civil, CHRU de StrasbourgStrasbourg, France.
Anne LejayEquipe d'accueil 3072, Faculté de Médecine, Fédération de Médecine Translationnelle, Université de StrasbourgStrasbourg, France; Service de Physiologie et d'Explorations Fonctionnelles, Pôle de Pathologie Thoracique, Nouvel Hôpital Civil, CHRU de StrasbourgStrasbourg, France.
Alain MeyerEquipe d'accueil 3072, Faculté de Médecine, Fédération de Médecine Translationnelle, Université de StrasbourgStrasbourg, France; Service de Physiologie et d'Explorations Fonctionnelles, Pôle de Pathologie Thoracique, Nouvel Hôpital Civil, CHRU de StrasbourgStrasbourg, France.
Michel KindoEquipe d'accueil 3072, Faculté de Médecine, Fédération de Médecine Translationnelle, Université de StrasbourgStrasbourg, France; Service de Chirurgie Cardio-Vasculaire, Pôle d'activité Médico-chirurgicale Cardiovasculaire, Nouvel Hôpital Civil, CHRU de StrasbourgStrasbourg, France.
Valérie WolffEquipe d'accueil 3072, Faculté de Médecine, Fédération de Médecine Translationnelle, Université de StrasbourgStrasbourg, France; Unité neurovasculaire, Hôpital de Hautepierre, CHRU de StrasbourgStrasbourg, France.
Jamal BouitbirDivision of Clinical Pharmacology and Toxicology, University Hospital Basel Basel, Switzerland.
Joffrey ZollEquipe d'accueil 3072, Faculté de Médecine, Fédération de Médecine Translationnelle, Université de StrasbourgStrasbourg, France; Service de Physiologie et d'Explorations Fonctionnelles, Pôle de Pathologie Thoracique, Nouvel Hôpital Civil, CHRU de StrasbourgStrasbourg, France.
Bernard GenyEquipe d'accueil 3072, Faculté de Médecine, Fédération de Médecine Translationnelle, Université de StrasbourgStrasbourg, France; Service de Physiologie et d'Explorations Fonctionnelles, Pôle de Pathologie Thoracique, Nouvel Hôpital Civil, CHRU de StrasbourgStrasbourg, France.
Hôpitaux Universitaires de Strasbourg · FRHôpital Civil, Strasbourg · FRUniversité de Strasbourg · FRUniversity Hospital of Basel · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Muscle injury resulting from ischemia-reperfusion largely aggravates patient prognosis but whether and how muscle phenotype modulates ischemia-reperfusion-induced mitochondrial dysfunction remains to be investigated. We challenged the hypothesis that glycolytic muscles are more prone to ischemia-reperfusion-induced injury than oxidative skeletal muscles. We therefore determined simultaneously the effect of 3 h of ischemia induced by aortic clamping followed by 2 h of reperfusion (IR,

Indexed as

antioxidantischemia-reperfusionmetabolic phenotypemitochondriamuscleoxidative stressperipheral arterial disease (PAD)sarcopenia

Identifiers

PMID28220081
PMCPMC5292410
OpenAlexW2586939323

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.