ArticleThe American journal of tropical medicine and hygiene2017
A New Handheld Device for the Detection of Falsified Medicines: Demonstration on Falsified Artemisinin-Based Therapies from the Field.
Article in The American journal of tropical medicine and hygiene, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
15 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Anti-malarial medicine quality field studies and surveys: a systematic review of screening technologies used and reporting of findings.Malaria journal · 2017Pooled it
- Transnational Criminal Enterprise: a Qualitative Social Network Analysis of the Production and Trade in Falsified Medicines.Archives europeennes de sociologie. European journal of sociology. Europaisches Archiv fur Soziologie · 2025Article
- Spectraformer: deep learning model for grain spectral qualitative analysis based on transformer structure.RSC advances · 2024Article
- Antimalarial stocking decisions among medicine retailers in Ghana: implications for quality management and control of malaria.BMJ global health · 2023Article
- Usefulness of medicine screening tools in the frame of pharmaceutical post-marketing surveillance.PloS one · 2023Article
- Comparing the return on investment of technologies to detect substandard and falsified amoxicillin: A Kenya case study.PloS one · 2023Article
- Article
- Adulteration Detection of Edible Bird's Nests Using Rapid Spectroscopic Techniques Coupled with Multi-Class Discriminant Analysis.Foods (Basel, Switzerland) · 2022Article
- Laboratory evaluation of twelve portable devices for medicine quality screening.PLoS neglected tropical diseases · 2021Article
- Evaluating Low-Cost Optical Spectrometers for the Detection of Simulated Substandard and Falsified Medicines.Applied spectroscopy · 2020Article
- Investigations into the Performance of a Novel Pocket-Sized Near-Infrared Spectrometer for Cheese Analysis.Molecules (Basel, Switzerland) · 2019Article
- Differentiation of Apple Varieties and Investigation of Organic Status Using Portable Visible Range Reflectance Spectroscopy.Sensors (Basel, Switzerland) · 2018Article
- Field detection devices for screening the quality of medicines: a systematic review.BMJ global health · 2018Article
- Evaluation of a miniaturized NIR spectrometer for cultivar identification: The case of barley, chickpea and sorghum in Ethiopia.PloS one · 2018Article
- Prevalence of substandard and falsified artemisinin-based combination antimalarial medicines on Bioko Island, Equatorial Guinea.BMJ global health · 2017Article
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
AbstractPoor-quality medicines are a major problem for health-care systems in resource-poor settings as identifying falsified medicines requires a complex laboratory infrastructure such as a Medicines Quality Control Laboratory. We report here an evaluation of a low-cost, handheld near-infrared spectrometer (NIRS) device by analyzing a library of artemisinin-based combination therapy (ACT) medicines to determine its usefulness as a drug-screening tool. The "SCiO" research prototype device was used to collect NIR spectra of a library of ACT and artesunate monotherapy medicine samples previously collected in Bioko Island and Equatorial Guinea and Kintampo, Ghana. The quality of these samples had been categorized as falsified, substandard, and quality assured based on the amount of stated active pharmaceutical ingredients detected using high-performance liquid chromatography photodiode array. Numerical analyses were performed on the NIR spectra to assess the usefulness of NIR to identify falsified and substandard medicines. The NIRS device was successful at detecting falsified medicines in all cases where the library contained both quality assured and falsified medicines of the same stated brand of medicines. The NIRS device was successful at identifying substandard amounts of artesunate but not amodiaquine in the ACT samples (
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