Evidence map›Paper›PMID 28219939›Full record

ArticleThe Biochemical journal2017

Peroxiredoxin 1 (Prx1) is a dual-function enzyme by possessing Cys-independent catalase-like activity.

Cen-Cen Sun, Wei-Ren Dong, Tong Shao, Jiang-Yuan Li, Jing Zhao, Li Nie, Li-Xin Xiang, Guan Zhu, Jian-Zhong Shao

Open access · bronzeAbstract readComparative Study
In one paragraph

Article in The Biochemical journal, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
1.8field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 35 citations in OpenAlex.

  1. Article
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  4. Recent Progress on Peroxidase Modification and Application.Applied biochemistry and biotechnology · 2024
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  14. Review
  15. Plant catalases as NO and HRedox biology · 2020
    Review
  16. Article
  17. Article
  18. Article
  19. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Cen-Cen SunCollege of Life Sciences, Zhejiang University, and Key Laboratory for Cell and Gene Engineering of Zhejiang Province, Hangzhou 310058, China.
Wei-Ren DongCollege of Life Sciences, Zhejiang University, and Key Laboratory for Cell and Gene Engineering of Zhejiang Province, Hangzhou 310058, China.
Tong ShaoCollege of Life Sciences, Zhejiang University, and Key Laboratory for Cell and Gene Engineering of Zhejiang Province, Hangzhou 310058, China.
Jiang-Yuan LiCollege of Life Sciences, Zhejiang University, and Key Laboratory for Cell and Gene Engineering of Zhejiang Province, Hangzhou 310058, China.
Jing ZhaoCollege of Life Sciences, Zhejiang University, and Key Laboratory for Cell and Gene Engineering of Zhejiang Province, Hangzhou 310058, China.
Li NieCollege of Life Sciences, Zhejiang University, and Key Laboratory for Cell and Gene Engineering of Zhejiang Province, Hangzhou 310058, China.
Li-Xin XiangCollege of Life Sciences, Zhejiang University, and Key Laboratory for Cell and Gene Engineering of Zhejiang Province, Hangzhou 310058, China shaojz@zju.edu.cn gzhu@cvm.tamu.edu xianglx@zju.edu.cn.
Guan ZhuCollege of Life Sciences, Zhejiang University, and Key Laboratory for Cell and Gene Engineering of Zhejiang Province, Hangzhou 310058, China shaojz@zju.edu.cn gzhu@cvm.tamu.edu xianglx@zju.edu.cn.
Jian-Zhong ShaoCollege of Life Sciences, Zhejiang University, and Key Laboratory for Cell and Gene Engineering of Zhejiang Province, Hangzhou 310058, China shaojz@zju.edu.cn gzhu@cvm.tamu.edu xianglx@zju.edu.cn.
Zhejiang University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Peroxiredoxin (Prx) was previously known as a Cys-dependent thioredoxin. However, we unexpectedly observed that Prx1 from the green spotted puffer fish

Indexed as

Models, MolecularTetraodontiformesAmino Acid SubstitutionAnimalsBinding SitesBiocatalysisCysteineFish ProteinsHEK293 CellsHumansHydrogen PeroxideMutagenesis, Site-DirectedMutationp38 Mitogen-Activated Protein KinasesPeroxiredoxinsPhosphorylationCysteineFish ProteinsHydrogen Peroxidep38 Mitogen-Activated Protein KinasesPeroxiredoxinsPRDX1 protein, humanReactive Oxygen SpeciesRecombinant Fusion ProteinsRecombinant Proteinscatalase-like activityperoxiredoxin 1 (Prx1)puffer fishROS

Identifiers

PMID28219939
PMCPMC5452528
OpenAlexW2589841578

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.