ArticleGut2018
Toxin-positive
Article in Gut, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
22 citing papers in PubMed, 36 citations in OpenAlex.
- Protocol to study recurrence of Clostridioides difficile infection in murine model with built-in colonization and contamination controls.STAR protocols · 2026Article
- Conventional, Gnotobiotic, and Humanized Microbiota Mouse Models of C. difficile Infection.Methods in molecular biology (Clifton, N.J.) · 2026Article
- Unravelling three-way interactions betweenJournal of medical microbiology · 2025Review
- The interplay between host immunity andmBio · 2025Review
- Protection against Clostridioides difficile disease by a naturally avirulent strain.Cell host & microbe · 2025Article
- Protection againstbioRxiv : the preprint server for biology · 2024Article
- Multimodal vaccination targeting the receptor binding domains ofMicrobiology spectrum · 2024Article
- Evidence for a Causal Role for Escherichia coli Strains Identified as Adherent-Invasive (AIEC) in Intestinal Inflammation.mSphere · 2023Article
- Dietary nano-selenium alleviated intestinal damage of juvenile grass carp (Animal nutrition (Zhongguo xu mu shou yi xue hui) · 2022Article
- The Butyrate-Producing BacteriumJournal of immunology (Baltimore, Md. : 1950) · 2021Article
- Article
- Detection and elimination of a novel non-toxigenicGut microbes · 2020Article
- The Initial Gut Microbiota and Response to Antibiotic Perturbation Influence Clostridioides difficile Clearance in Mice.mSphere · 2020Article
- Outbreaks of Typhlocolitis Caused by Hypervirulent Group ST1Comparative medicine · 2020Article
- IL-17-producing γδ T cells protect against Clostridium difficile infection.The Journal of clinical investigation · 2020Article
- Plasmid-mediated metronidazole resistance in Clostridioides difficile.Nature communications · 2020Article
- Synthetic Oligosaccharide-Based Vaccines Protect Mice fromACS chemical biology · 2019Article
- Outbreak of Murine Infection withmSphere · 2019Article
- [Efficacy of real-time PCR for detecting Clostridium difficile infection: comparison with enzyme-linked fluorescent spectroscopy-based approaches].Nan fang yi ke da xue xue bao = Journal of Southern Medical University · 2017Article
- Genome Sequence of a Toxin-PositiveGenome announcements · 2017Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 4 institutions in 2 countries.
Funding
Abstract
objective
designMice purchased from multiple vendors and repeatedly testing negative for this pathogen by quantitative PCR bloomed
resultsWhole-genome sequencing revealed that LEM1 and VPI10463 shared 95% of their genes, including all known virulence genes. In contrast to VPI10463, LEM1 did not induce overt disease when administered to antibiotic-treated or germ-free mice, even at high doses. Rather, blooms of LEM1 correlated with survival following VPI10463 inoculation, and exogenous administration of LEM1 before or shortly following VPI10463 inoculation prevented
conclusionsThese results highlight the difficulty of determining whether individual cases of
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.