Evidence map›Paper›PMID 28219860›Full record

ArticleNan fang yi ke da xue xue bao = Journal of Southern Medical University2016

[Salidroside protects PC12 cells from H

Zhi-Lin Qi, Yin-Hua Liu, Shi-Mei Qi, Lie-Feng Ling, Zun-Yong Feng, Qiang Li

Abstract read
In one paragraph

Article in Nan fang yi ke da xue xue bao = Journal of Southern Medical University, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
0.9field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it, 11 citations in OpenAlex.

  1. StandardizedFrontiers in pharmacology · 2025
    Pooled it
  2. Secondary Metabolites fromPharmaceuticals (Basel, Switzerland) · 2025
    Article
  3. Review
  4. Article
  5. Article
  6. [Aloin induces apoptosisNan fang yi ke da xue xue bao = Journal of Southern Medical University · 2018
    Article
  7. Article
  8. [Quinalizarin induces apoptosis in gastric cancer AGS cells via MAPK and Akt signaling pathway].Nan fang yi ke da xue xue bao = Journal of Southern Medical University · 2017
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Zhi-Lin QiDepartment of Biochemistry1,Wannan Medical College, Wuhu 241002, China; 3Anhui Provincial Key Laboratory of Active Biological Macro-molecules, Wuhu 241002, China. E-mail: 422627721@qq.com.
Yin-Hua Liu
Shi-Mei Qi
Lie-Feng Ling
Zun-Yong Feng
Qiang Li
Wannan Medical College · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo investigate the molecular mechanism by which salidroside protects PC12 cells from H

methodsPC12 cells cultured in DMEM supplemented with 10% horse serum and 5% fetal bovine serum were pretreated with different doses of salidroside for 2 h and then stimulated with H

resultsSalidroside dose-dependently suppressed cell apoptosis, lowered phosphorylation levels of p38, ERK and JNK, inhibited the production of ROS, reduced the binding between gp91

conclusionSalidroside protects PC12 cells from H

Indexed as

ApoptosisAnimalsCaspase 3GlucosidesHydrogen PeroxideMAP Kinase Signaling SystemMembrane GlycoproteinsNADPH Oxidase 2NADPH OxidasesNeuroprotective AgentsPC12 CellsPhenolsPhosphorylationRatsReactive Oxygen SpeciesCaspase 3Cybb protein, ratGlucosidesHydrogen PeroxideMembrane GlycoproteinsNADPH Oxidase 2NADPH OxidasesNeuroprotective AgentsPhenolsReactive Oxygen Speciesrhodioloside

Identifiers

PMID28219860
PMCPMC6779671
OpenAlexW2972572593

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.