Evidence map›Paper›PMID 28219113›Full record

ArticlePsycho-oncology2017

Personality, coping, and social support as predictors of long-term quality-of-life trajectories in older breast cancer survivors: CALGB protocol 369901 (Alliance).

Estrella Durá-Ferrandis, Jeanne S Mandelblatt, Jonathan Clapp, George Luta, LeighAnne Faul, Gretchen Kimmick, Harvey Jay Cohen, Rachel L Yung, Arti Hurria

Registry-linked trialAbstract read
In one paragraph

Article in Psycho-oncology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04219267 (Effectiveness of Character Strengths-based Intervention in Enhancing Self-esteem, Quality of Life and Alleviating Depression Among Breast Cancer Patients), which is not on this map. Cited by 45 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
45citing papers in PubMed, 3 pooled it
4.2field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04219267 nacompletednot on this mapstarted 2020, after this paper: background citation

Effectiveness of Character Strengths-based Intervention in Enhancing Self-esteem, Quality of Life and Alleviating Depression Among Breast Cancer Patients: A Randomized Controlled Study

TypeinterventionalSponsorChinese University of Hong KongRan2020 to 2020Enrolled122ConditionsBreast CancerArmscharacter strengths-based intervention, early memories
3 · Its place in the literature

Who cites it

45 citing papers in PubMed, 3 syntheses or guidelines pooled it, 106 citations in OpenAlex.

  1. Pooled it
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  10. Health-related quality of life trajectories among older breast cancer survivors: a SEER-MHOS analysis.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2025
    Article
  11. Coping Strategies and Health-Related Quality of Life in Breast Cancer Survivors.European journal of investigation in health, psychology and education · 2025
    Article
  12. Article
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  14. Observational
  15. Physical activity and quality of life among breast cancer survivors: Pink SWAN.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2025
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  16. Article
  17. Article
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  20. Physical health-related quality of life trajectories over two years following breast cancer diagnosis in older women: a secondary analysis.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 6 institutions in 2 countries.

Estrella Durá-FerrandisPolibienestar Research Institute, University of Valencia, Valencia, Spain.ORCID http://orcid.org/0000-0002-9958-408X
Jeanne S MandelblattDepartment of Oncology, Georgetown University School of Medicine and Lombardi Comprehensive Cancer Center, Prevention and Control Program, Washington, DC, USA.
Jonathan ClappDepartment of Oncology, Georgetown University School of Medicine and Lombardi Comprehensive Cancer Center, Prevention and Control Program, Washington, DC, USA.ORCID http://orcid.org/0000-0002-8058-5808
George LutaDepartment of Biostatistics, Bioinformatics and Biomathematics, Georgetown University Medical Center, and Lombardi Comprehensive Cancer Center, Prevention and Control Program, Washington, DC, USA.ORCID http://orcid.org/0000-0001-9013-2207
LeighAnne FaulDepartment of Oncology, Georgetown University School of Medicine and Lombardi Comprehensive Cancer Center, Prevention and Control Program, Washington, DC, USA.
Gretchen KimmickDepartment of Oncology, Duke Cancer Institute, Duke University Medical Center, Durham, NC, USA.
Harvey Jay CohenDepartment of Medicine, Center for the Study of Aging and Human Development, Duke University Medical Center, Durham, NC, USA.
Rachel L YungDana-Farber/Partners Cancer Care, Boston, MS, USA.
Arti HurriaDepartment of Medical Oncology and Therapeutics Research, City of Hope Comprehensive Cancer Center, Duarte, CA, USA.
Georgetown University · USCancerCare · USCity of Hope · USDuke Medical Center · USDuke University · USUniversitat de València · ES

Funding

Member Site CoreU10CA180821 · NCI · BRIGHAM AND WOMEN'S HOSPITAL · PI Evanthia Galanis · 2014 to 2026
$177.3M
CANCER AND LEUKEMIA GROUP B MINORITY SATELLITE SUPPLEMENU10CA031946 · NCI · UNIVERSITY OF CHICAGO · PI BERTAGNOLLI, MONICA M · 1985 to 2013
$158.4M
Collaborations and NCORP Collective ManagementUG1CA189823 · NCI · MAYO CLINIC ROCHESTER · PI Evanthia Galanis, Olwen Hahn · 2014 to 2026
$120.6M
Tissue Culture Shared ResourceP30CA051008 · NCI · GEORGETOWN UNIVERSITY · PI Louis M Weiner · 1990 to 2026
$71.5M
CANCER &LEUKEMIA GROUP B STATISTICAL CENTERU10CA033601 · NCI · UNIVERSITY OF NEBRASKA MEDICAL CENTER · PI SARGENT, DANIEL J. · 1985 to 2013
$69.4M
Training and Career Development CoreU54CA132378 · NCI · CITY COLLEGE OF NEW YORK · PI Tim Alan Ahles, ADRIANA ESPINOSA · 2008 to 2026
$28.9M
Training and Career Development and Education CoreU54CA137788 · NCI · SLOAN-KETTERING INST CAN RESEARCH · PI Daniel Alan Heller · 2008 to 2026
$28.1M
OLDER BREAST CANCER PATIENTS: RISK FOR COGNITIVE DECLINER01CA129769 · NCI · GEORGETOWN UNIVERSITY · PI AHLES, TIM ALAN, MANDELBLATT, JEANNE · 2009 to 2020
$7.3M
Bio-behavioral Research At The Intersection of Cancer and AgingR35CA197289 · NCI · GEORGETOWN UNIVERSITY · PI MANDELBLATT, JEANNE · 2015 to 2021
$6.2M
NIA CALGB - Foreign AccrualU10CA084131 · NCI · GEORGETOWN UNIVERSITY · PI MANDELBLATT, JEANNE · 2001 to 2005
$3.2M
Who Cares For Older Breast Cancer Surivors And How Does It Affect Quality?R01CA127617 · NCI · GEORGETOWN UNIVERSITY · PI MANDELBLATT, JEANNE · 2008 to 2012
$3.2M
Using Physiological Age to Predict Chemotherapy ToxicityR01CA124924 · NCI · GEORGETOWN UNIVERSITY · PI MANDELBLATT, JEANNE · 2007 to 2011
$2.9M
NCI NIH HHS K05 CA096940NCI NIH HHS P30 CA051008NCI NIH HHS R01 CA124924NCI NIH HHS R01 CA127617NCI NIH HHS R01 CA129769NCI NIH HHS R35 CA197289NCI NIH HHS U10 CA031946NCI NIH HHS U10 CA033601NCI NIH HHS U10 CA084131NCI NIH HHS U10 CA180821NCI NIH HHS U54 CA132378NCI NIH HHS U54 CA137788NCI NIH HHS UG1 CA189823
6 · The paper itself

Abstract

backgroundTo determine long-term quality-of-life (QOL) trajectories among breast cancer survivors aged 65+ (older) evaluating the effects of personality and social support.

methodsOlder women (N = 1280) newly examined with invasive, nonmetastatic breast cancer completed baseline assessments. Follow-up data were collected 6 and 12 months later and then annually for up to 7 years (median 4.5 years). Quality of life was assessed using EORTC-QLQ-C30 emotional, physical, and cognitive scales. Optimism (Life Orientation Test), Coping (Brief COPE), and social support (Medical Outcomes Study) were assessed at baseline. Group-based trajectory modeling identified QOL trajectories; multinomial regression evaluated effects of predictors on trajectory groups. Age, education, systemic therapy, comorbidity, and reported precancer function (SF-12) were considered as controlling variables.

resultsThree trajectories were identified for each QOL domain: "maintained high," "phase shift" (lower but parallel scores to "maintained high" group), and "accelerated decline" (lowest baseline scores and steepest decline). Accelerated decline in emotional, physical, and cognitive function was seen in 6.9%, 31.8%, and 7.6% of older survivors, respectively. Maladaptive coping and lower social support increased adjusted odds of being in the accelerated decline group for all QOL domains; lower optimism was only related to decline in emotional function. Chemotherapy was related to physical and cognitive but not emotional function trajectories.

conclusionsPersonality and social resources affect the course of long-term emotional well-being of older breast cancer survivors; treatment is more important for physical and cognitive than emotional function. Early identification of those vulnerable to deterioration could facilitate clinical and psychological support.

Indexed as

Adaptation, PsychologicalPersonalitySocial SupportAgedBreast NeoplasmsCancer SurvivorsCognitionComorbidityFemaleHumansMental HealthMiddle AgedQuality of LifeSurvivorsWatchful Waitingcancerlong-term quality-of-life trajectoriesolder breast cancer survivorsoncologypersonalitysocial support

Identifiers

PMID28219113
PMCPMC5563496
OpenAlexW2589552976

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.